PAWR and SLC5A7

Number of citations of the paper that reports this interaction (PMID 15090548)
4

Data Source:
HPRD (in vivo, in vitro)

		PAWR	SLC5A7
Gene Name		PRKC, apoptosis, WT1, regulator	solute carrier family 5 (sodium/choline cotransporter), member 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Actin Filament Plasma Membrane Actin Cytoskeleton	Plasma Membrane Integral Component Of Membrane Neuronal Cell Body
	Molecular Function	Transcription Corepressor Activity Actin Binding Protein Binding Enzyme Binding Leucine Zipper Domain Binding	Choline:sodium Symporter Activity Choline Transmembrane Transporter Activity Choline Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of B Cell Proliferation Interleukin-2 Biosynthetic Process Negative Regulation Of T Cell Proliferation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of T Cell Receptor Signaling Pathway Actin Filament Bundle Assembly Apoptotic Signaling Pathway	Sodium Ion Transport Synaptic Transmission Neurotransmitter Secretion Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Acetylcholine Biosynthetic Process Choline Transport Transmembrane Transport
Pathways			Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions		17 interactors: AATF ATP5C1 DAPK3 DRD2 FBXO45 HSPA5 PML PRKCZ RRAS2 SLC5A7 SPSB1 SPSB2 SPSB4 SQSTM1 TFPT THAP1 WT1	1 interactors: PAWR
Entrez ID		5074	60482
HPRD ID		09051	12294
Ensembl ID			ENSG00000115665
Uniprot IDs		Q96IZ0	F5H382 Q9GZV3
PDB IDs		2JK9
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Apoptotic Signaling Pathway Cellular Response To Stimulus Signaling Cell Communication Signal Transduction Negative Regulation Of Translation Apoptotic Process Programmed Cell Death Regulation Of Protein Metabolic Process Cell Death Death Response To Stimulus Cellular Metabolic Process Response To Organic Substance Cellular Response To Organic Substance Regulation Of Mitotic Cell Cycle Response To Stress Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Long-term Memory Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Response To Interleukin-4 Cellular Response To Stress Negative Regulation Of Cell Death Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Response To Interleukin-4 Protein Ubiquitination Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cell Migration Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Morphogenesis Of A Branching Structure Response To Growth Factor Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Translation In Response To Oxidative Stress	Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Interleukin-2 Biosynthetic Process Regulation Of Amyloid Precursor Protein Biosynthetic Process Interleukin-2 Production Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Negative Regulation Of B Cell Proliferation Negative Regulation Of T Cell Receptor Signaling Pathway Cytokine Biosynthetic Process Regulation Of Glycoprotein Biosynthetic Process Cytokine Metabolic Process Negative Regulation Of B Cell Activation Regulation Of T Cell Receptor Signaling Pathway Regulation Of B Cell Proliferation Negative Regulation Of T Cell Proliferation Actin Filament Bundle Assembly Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Lymphocyte Activation Negative Regulation Of Cell-cell Adhesion Cytokine Production Regulation Of T Cell Proliferation Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell Adhesion Regulation Of T Cell Activation Actin Filament Organization Apoptotic Signaling Pathway
Tagcloud ?		aggravating airway airways asthma asthmatic ats cawr coexisting expiratory fev1 forced fvc gastroesophageal gerd hz impulse ios ninety oscillometry pef plethysmography presences reflux representative sec severity tawr verified vital	bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto laptm5 mismatch mortem omnibus ontology paired ppi ptprc spliceosome splicing transesterification
Tagcloud (Difference) ?		aggravating airway airways asthma asthmatic ats cawr coexisting expiratory fev1 forced fvc gastroesophageal gerd hz impulse ios ninety oscillometry pef plethysmography presences reflux representative sec severity tawr verified vital	bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto laptm5 mismatch mortem omnibus ontology paired ppi ptprc spliceosome splicing transesterification
Tagcloud (Intersection) ?