PAWR and ATP5C1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PAWR	ATP5C1
Gene Name		PRKC, apoptosis, WT1, regulator	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Actin Filament Plasma Membrane Actin Cytoskeleton	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane Extracellular Vesicular Exosome
	Molecular Function	Transcription Corepressor Activity Actin Binding Protein Binding Enzyme Binding Leucine Zipper Domain Binding	ATPase Activity Transmembrane Transporter Activity Poly(A) RNA Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of B Cell Proliferation Interleukin-2 Biosynthetic Process Negative Regulation Of T Cell Proliferation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of T Cell Receptor Signaling Pathway Actin Filament Bundle Assembly Apoptotic Signaling Pathway	Oxidative Phosphorylation ATP Biosynthetic Process Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions		17 interactors: AATF ATP5C1 DAPK3 DRD2 FBXO45 HSPA5 PML PRKCZ RRAS2 SLC5A7 SPSB1 SPSB2 SPSB4 SQSTM1 TFPT THAP1 WT1	23 interactors: APP ATP5A1 ATP5B CA12 CCND3 CCT7 CHMP2B DPP3 EGFR ELOF1 GDPD2 ITIH2 MED15 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTN SERPINA1 ZNF337
Entrez ID		5074	509
HPRD ID		09051	00156
Ensembl ID			ENSG00000165629
Uniprot IDs		Q96IZ0	P36542 Q8TAS0
PDB IDs		2JK9
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Apoptotic Signaling Pathway Cellular Response To Stimulus Signaling Cell Communication Signal Transduction Negative Regulation Of Translation Apoptotic Process Programmed Cell Death Regulation Of Protein Metabolic Process Cell Death Death Response To Stimulus Cellular Metabolic Process Response To Organic Substance Cellular Response To Organic Substance Regulation Of Mitotic Cell Cycle Response To Stress Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Long-term Memory Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Response To Interleukin-4 Cellular Response To Stress Negative Regulation Of Cell Death Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Response To Interleukin-4 Protein Ubiquitination Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cell Migration Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Morphogenesis Of A Branching Structure Response To Growth Factor Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Translation In Response To Oxidative Stress	Mitochondrial ATP Synthesis Coupled Proton Transport Respiratory Electron Transport Chain Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Electron Transport Chain ATP Metabolic Process ATP Synthesis Coupled Proton Transport Cellular Respiration ATP Biosynthetic Process Alkanesulfonate Metabolic Process Response To Methanol Purine Nucleoside Metabolic Process Ion Homeostasis Nucleotide Metabolic Process Negative Regulation Of Endopeptidase Activity Learning Or Memory Negative Regulation Of Peptidase Activity ATP Hydrolysis Coupled Proton Transport Synaptic Growth At Neuromuscular Junction Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Response To Triglyceride Astrocyte Activation Platelet Degranulation Purine Ribonucleoside Monophosphate Biosynthetic Process Ossification Positive Regulation Of Cell Cycle Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cognition Ribonucleotide Metabolic Process Nucleoside Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Nucleobase-containing Small Molecule Metabolic Process Purine Nucleotide Metabolic Process Regulation Of ERBB Signaling Pathway Negative Regulation Of Dendritic Spine Morphogenesis Collateral Sprouting In Absence Of Injury Nucleoside Triphosphate Biosynthetic Process Ribose Phosphate Metabolic Process Cell Activation Ribonucleoside Monophosphate Biosynthetic Process Small Molecule Metabolic Process Activation Of Phospholipase A2 Activity Response To Chromate Negative Regulation Of Proteolysis Cellular Metabolic Process Regulation Of Catalytic Activity Nucleobase-containing Compound Metabolic Process Nucleoside Monophosphate Biosynthetic Process Negative Regulation Of Protein Processing Cellular Localization
Tagcloud ?		aggravating airway airways asthma asthmatic ats cawr coexisting expiratory fev1 forced fvc gastroesophageal gerd hz impulse ios ninety oscillometry pef plethysmography presences reflux representative sec severity tawr verified vital	3xflag compatible created creating ddost deleted dissociated envelope immunolocalization knock mammals persists phosphatases pp1 ppp1ca ppp1cb ppp1cc ppp1cc1 ppp1cc2 reciprocal sbp sedimentation spermatogenesis spermatogenic splice tagged tandem testis ubiquitously
Tagcloud (Difference) ?		aggravating airway airways asthma asthmatic ats cawr coexisting expiratory fev1 forced fvc gastroesophageal gerd hz impulse ios ninety oscillometry pef plethysmography presences reflux representative sec severity tawr verified vital	3xflag compatible created creating ddost deleted dissociated envelope immunolocalization knock mammals persists phosphatases pp1 ppp1ca ppp1cb ppp1cc ppp1cc1 ppp1cc2 reciprocal sbp sedimentation spermatogenesis spermatogenic splice tagged tandem testis ubiquitously
Tagcloud (Intersection) ?