SPSB2 and DDX4

Number of citations of the paper that reports this interaction (PMID 20561531)
9

Data Source:
BioGRID (unspecified method)

		SPSB2	DDX4
Gene Name		splA/ryanodine receptor domain and SOCS box containing 2	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm	Nucleus Cytoplasm Chromatoid Body Perinuclear Region Of Cytoplasm Pi-body PiP-body
	Molecular Function	Molecular_function Protein Binding	Nucleic Acid Binding Helicase Activity ATP Binding
	Biological Process	Biological_process Protein Ubiquitination Intracellular Signal Transduction	Male Meiosis I Multicellular Organismal Development Spermatogenesis Gene Expression Sperm Motility Regulation Of Protein Localization PiRNA Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	PIWI-interacting RNA (piRNA) biogenesis Regulatory RNA pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP DDX4 GALNT15 NOS2 PAWR PRMT1	5 interactors: PIWIL2 RANBP9 SPSB1 SPSB2 SPSB4
Entrez ID		84727	54514
HPRD ID		13610	05593
Ensembl ID		ENSG00000111671	ENSG00000152670
Uniprot IDs		B7Z4W1 Q99619	Q9NQI0
PDB IDs		3EMW
Enriched GO Terms of Interacting Partners?		Sexual Reproduction Reproduction Reproductive Process Spermatogenesis Male Gamete Generation Gamete Generation Cell Development Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Synaptic Growth At Neuromuscular Junction Negative Regulation Of Cell Differentiation Collateral Sprouting In Absence Of Injury Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Negative Regulation Of Megakaryocyte Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Peptidyl-cysteine S-nitrosylation Interleukin-2 Biosynthetic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Germ-line Stem Cell Maintenance Axon Choice Point Recognition Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Amyloid Precursor Protein Biosynthetic Process Regulation Of Translation Interleukin-2 Production Arginine Catabolic Process Single Organism Reproductive Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Remodeling Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Guanylate Cyclase Activity Regulation Of Immune System Process Peptidyl-arginine N-methylation Regulation Of Cellular Respiration Developmental Process Protein Metabolic Process Histone H4-R3 Methylation Positive Regulation Of Glycoprotein Biosynthetic Process Negative Regulation Of Immune System Process Nitric Oxide Biosynthetic Process Organelle Organization Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Glycoprotein Metabolic Process RNA Metabolic Process Cellular Protein Modification Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of B Cell Proliferation Innate Immune Response In Mucosa Histone Arginine Methylation	Protein Ubiquitination Protein Modification By Small Protein Conjugation RNA 5'-end Processing Positive Regulation Of Meiosis I Germ-line Stem Cell Maintenance Regulation Of Meiosis I
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Tagcloud (Difference) ?			122c 2012cb944901 9qh azoospermia blimp1 dazl declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
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