GLYR1 and NSD3

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		GLYR1	NSD3
Description		glyoxylate reductase 1 homolog	nuclear receptor binding SET domain protein 3
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GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm Chromosome Cytosol	Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Nucleosome Binding Histone Binding NADP Binding NAD Binding Chromatin-protein Adaptor Activity	Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K36 Methyltransferase Activity Histone H3K27 Methyltransferase Activity Transcription Regulator Activator Activity Histone H3 Methyltransferase Activity Histone H3K4 Dimethyltransferase Activity Histone H3K27 Trimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity
	Biological Process	Transcription Initiation-coupled Chromatin Remodeling Transcription Elongation-coupled Chromatin Remodeling	Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Methylation Positive Regulation Of DNA-templated Transcription
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Cancer ( 29299148) Night sleep phenotypes ( 27126917)
Interacting Genes		14 interacting genes: ARL16 CCNC CDKN2D CFAP206 CLIC3 EIF1AD FHL2 FXR1 GEMIN4 H3-4 H3C1 KDM1A NSD3 NTMT1	41 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		84656	54904
HPRD ID		17625	06155
Ensembl ID		ENSG00000140632	ENSG00000147548
Uniprot IDs		Q49A26 Q9NZ78	Q9BZ95
PDB IDs		2UYY 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25	2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR 7JYN
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ribonucleoprotein Complex Binding Chromatin Remodeling Chromatin Organization N-terminal Protein N-methyltransferase Activity N-terminal Protein Amino Acid Methylation Histone Methyltransferase Activity N-terminal Peptidyl-serine Dimethylation N-terminal Peptidyl-proline Dimethylation N-terminal Peptidyl-serine Trimethylation N-terminal Peptidyl-glycine Methylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity A Axonemal Microtubule Atrial Cardiac Muscle Cell Development Protein-disulfide Reductase (glutathione) Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Cyclin D2-CDK4 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Translational Initiation Chromosome Structural Constituent Of Chromatin Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone H3K27 Trimethyltransferase Activity	Nucleus Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Replicative Senescence Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process PML Body Euchromatin Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Negative Regulation Of Biosynthetic Process Regulation Of Programmed Cell Death Negative Regulation Of Transcription By RNA Polymerase II Protein K63-linked Ubiquitination Apoptotic Signaling Pathway Regulation Of Intracellular Signal Transduction Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Protein Localization To Nucleus Cell Differentiation Chromosome, Telomeric Region Cellular Developmental Process Chromatin Remodeling DNA-binding Transcription Factor Activity Pexophagy Negative Regulation Of B Cell Proliferation
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