WHSC1L1 and ZNF557

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		WHSC1L1	ZNF557
Gene Name		Wolf-Hirschhorn syndrome candidate 1-like 1	zinc finger protein 557
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K4 Specific) Histone Methyltransferase Activity (H3-K27 Specific)	DNA Binding Metal Ion Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Histone Methylation Negative Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K27 Methylation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines	Generic Transcription Pathway
Drugs
Diseases
GWAS		Schizophrenia ( 22037555)
Protein-Protein Interactions		17 interactors: CBX3 CBX5 DAXX DOCK7 ETV3 GLYR1 H3F3C HIST1H1A HOXC4 MLLT6 MNDA SEPT6 SLU7 SPAG8 STAC3 UBE2I ZNF557	6 interactors: PRMT6 SMAD9 SMYD3 SUV39H1 SUV39H2 WHSC1L1
Entrez ID		54904	79230
HPRD ID		06155	15840
Ensembl ID		ENSG00000147548	ENSG00000130544
Uniprot IDs		B7ZL11 Q9BZ95	Q8N988
PDB IDs		2DAQ 4GND 4GNE 4GNF 4GNG
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cell Division Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Establishment Of Neuroblast Polarity Cytokinesis Nucleosome Assembly MRNA 3'-splice Site Recognition Transcription, DNA-templated Chromatin Assembly RNA Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Gene Expression Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling DNA Packaging Nucleobase-containing Compound Metabolic Process	Histone Methylation Protein Methylation Histone Lysine Methylation Peptidyl-lysine Methylation Histone Modification Methylation Chromatin Modification Chromatin Organization Peptidyl-lysine Modification Histone H3-K9 Dimethylation Peptidyl-amino Acid Modification Chromosome Organization Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Cellular Protein Modification Process Negative Regulation Of Circadian Rhythm Histone H3-K9 Methylation Peptidyl-lysine Trimethylation Histone H3-K9 Modification Negative Regulation Of Cellular Metabolic Process Response To Hypoxia Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Metabolic Process Organelle Organization Regulation Of Circadian Rhythm RNA Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Histone H3-R2 Methylation Chromatin Assembly Or Disassembly Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Difference) ?		aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Intersection) ?