WHSC1L1 and MNDA

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		WHSC1L1	MNDA
Gene Name		Wolf-Hirschhorn syndrome candidate 1-like 1	myeloid cell nuclear differentiation antigen
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K4 Specific) Histone Methyltransferase Activity (H3-K27 Specific)	DNA Binding Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Histone Methylation Negative Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K27 Methylation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Schizophrenia ( 22037555)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		17 interactors: CBX3 CBX5 DAXX DOCK7 ETV3 GLYR1 H3F3C HIST1H1A HOXC4 MLLT6 MNDA SEPT6 SLU7 SPAG8 STAC3 UBE2I ZNF557	9 interactors: CDK1 CDK2 HOXB2 PRMT6 PRMT7 RB1 RBL2 TP53 WHSC1L1
Entrez ID		54904	4332
HPRD ID		06155	15932
Ensembl ID		ENSG00000147548	ENSG00000163563
Uniprot IDs		B7ZL11 Q9BZ95	P41218 Q5VUU6
PDB IDs		2DAQ 4GND 4GNE 4GNF 4GNG	2DBG
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cell Division Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Establishment Of Neuroblast Polarity Cytokinesis Nucleosome Assembly MRNA 3'-splice Site Recognition Transcription, DNA-templated Chromatin Assembly RNA Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Gene Expression Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling DNA Packaging Nucleobase-containing Compound Metabolic Process	Chromatin Organization Chromosome Organization Chromatin Modification Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Negative Regulation Of Mitotic Cell Cycle Ras Protein Signal Transduction Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Transcription, DNA-templated Glial Cell Apoptotic Process RNA Biosynthetic Process Mitotic Cell Cycle Histone H4-R3 Methylation Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Localization To Chromosome, Centromeric Region Peptidyl-arginine N-methylation Regulation Of Cell Cycle Histone Methylation Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Histone Arginine Methylation DNA Metabolic Process Peptidyl-arginine Methylation DNA Damage Checkpoint RNA Metabolic Process G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Tagcloud ?		aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified	adds capabilities cg challenging comparability confirming cytogenetics cytomorphology cytopenic details diagnostics dimg dimm discriminating dyspoiesis giving grades granulocytes investigator mfc mfi monocytes multiparameter myelomonocytic outlined panels percentages upcoming weakly
Tagcloud (Difference) ?		aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified	adds capabilities cg challenging comparability confirming cytogenetics cytomorphology cytopenic details diagnostics dimg dimm discriminating dyspoiesis giving grades granulocytes investigator mfc mfi monocytes multiparameter myelomonocytic outlined panels percentages upcoming weakly
Tagcloud (Intersection) ?