NSD3 and MNDA

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		NSD3	MNDA
Description		nuclear receptor binding SET domain protein 3	myeloid cell nuclear differentiation antigen
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Azurophil Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K36 Methyltransferase Activity Histone H3K27 Methyltransferase Activity Transcription Regulator Activator Activity Histone H3 Methyltransferase Activity Histone H3K4 Dimethyltransferase Activity Histone H3K27 Trimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity	DNA Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Methylation Positive Regulation Of DNA-templated Transcription	Activation Of Innate Immune Response Cellular Defense Response DNA Damage Response Negative Regulation Of B Cell Proliferation Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway
Pathways		PKMTs methylate histone lysines	Neutrophil degranulation
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)
Interacting Genes		41 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557	14 interacting genes: CDK1 CDK2 CEBPA CRK FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53
Entrez ID		54904	4332
HPRD ID		06155	15932
Ensembl ID		ENSG00000147548	ENSG00000163563
Uniprot IDs		Q9BZ95	P41218 Q5VUU6
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR 7JYN	2DBG 5H7Q 5WPZ 8I6K
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Replicative Senescence Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process PML Body Euchromatin Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Negative Regulation Of Biosynthetic Process Regulation Of Programmed Cell Death Negative Regulation Of Transcription By RNA Polymerase II Protein K63-linked Ubiquitination Apoptotic Signaling Pathway Regulation Of Intracellular Signal Transduction Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Protein Localization To Nucleus Cell Differentiation Chromosome, Telomeric Region Cellular Developmental Process Chromatin Remodeling DNA-binding Transcription Factor Activity Pexophagy Negative Regulation Of B Cell Proliferation	Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Transcription Regulator Complex Negative Regulation Of Cell Cycle Process Chromatin Organization Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Chromatin Remodeling Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Phase Transition Cyclin-dependent Protein Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Intracellular Signaling Cassette Histone Methyltransferase Activity Regulation Of Lipid Kinase Activity Nucleoplasm Regulation Of Transcription By RNA Polymerase II Rb-E2F Complex Glial Cell Apoptotic Process Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Nucleus Histone Kinase Activity Chromatin Cell Population Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of MiRNA Processing Regulation Of Cell Cycle Process Cellular Senescence DNA-templated Transcription Cellular Response To Xenobiotic Stimulus Regulation Of Hemopoiesis Protein-arginine N-methyltransferase Activity Mitotic DNA Damage Checkpoint Signaling Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Ras Protein Signal Transduction Regulation Of Cell Development G1/S Transition Of Mitotic Cell Cycle
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