GLYR1 and NTMT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GLYR1	NTMT1
Description		glyoxylate reductase 1 homolog	N-terminal Xaa-Pro-Lys N-methyltransferase 1
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GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm Chromosome Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Nucleosome Binding Histone Binding NADP Binding NAD Binding Chromatin-protein Adaptor Activity	Protein Binding Methyltransferase Activity Protein Methyltransferase Activity Transferase Activity Histone Methyltransferase Activity N-terminal Protein N-methyltransferase Activity
	Biological Process	Transcription Initiation-coupled Chromatin Remodeling Transcription Elongation-coupled Chromatin Remodeling	Chromatin Remodeling Spindle Organization Chromosome Segregation N-terminal Peptidyl-glycine Methylation N-terminal Peptidyl-proline Dimethylation Methylation N-terminal Peptidyl-serine Dimethylation N-terminal Peptidyl-serine Trimethylation
Pathways
Drugs
Diseases
GWAS		Cancer ( 29299148) Night sleep phenotypes ( 27126917)
Interacting Genes		14 interacting genes: ARL16 CCNC CDKN2D CFAP206 CLIC3 EIF1AD FHL2 FXR1 GEMIN4 H3-4 H3C1 KDM1A NSD3 NTMT1	7 interacting genes: APP DDB2 DIS3 GLYR1 HNRNPD IKBKG RCC1
Entrez ID		84656	28989
HPRD ID		17625	10628
Ensembl ID		ENSG00000140632	ENSG00000148335
Uniprot IDs		Q49A26 Q9NZ78	Q9BV86 S4R338
PDB IDs		2UYY 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25	2EX4 5CVD 5CVE 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 6DTN 6KDQ 6PVA 6PVB 6WH8 6WJ7 7K3D 7SS1 7U1M
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ribonucleoprotein Complex Binding Chromatin Remodeling Chromatin Organization N-terminal Protein N-methyltransferase Activity N-terminal Protein Amino Acid Methylation Histone Methyltransferase Activity N-terminal Peptidyl-serine Dimethylation N-terminal Peptidyl-proline Dimethylation N-terminal Peptidyl-serine Trimethylation N-terminal Peptidyl-glycine Methylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity A Axonemal Microtubule Atrial Cardiac Muscle Cell Development Protein-disulfide Reductase (glutathione) Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Cyclin D2-CDK4 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Translational Initiation Chromosome Structural Constituent Of Chromatin Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone H3K27 Trimethyltransferase Activity	Positive Regulation Of Catabolic Process Chromatin Binding Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Nucleosome Binding Protein-containing Complex Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium DNA Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Heterodimerization Activity Chromatin Hepatocyte Dedifferentiation Cellular Response To Putrescine Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Positive Regulation Of Protein Import Nucleoplasm MRNA Destabilization RNA Destabilization Circadian Regulation Of Translation Nuclear MRNA Surveillance Of MRNA 3'-end Processing PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of MRNA Catabolic Process Linear Polyubiquitin Binding Post-transcriptional Regulation Of Gene Expression Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Chromosome
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