NSD3 and IVNS1ABP

		NSD3	IVNS1ABP
Description		nuclear receptor binding SET domain protein 3	influenza virus NS1A binding protein
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K36 Methyltransferase Activity Histone H3K27 Methyltransferase Activity Transcription Regulator Activator Activity Histone H3 Methyltransferase Activity Histone H3K4 Dimethyltransferase Activity Histone H3K27 Trimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Methylation Positive Regulation Of DNA-templated Transcription	Transcription By RNA Polymerase III MRNA Processing RNA Splicing Response To Virus Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Lead levels ( 26025379)
Interacting Genes		41 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557	11 interacting genes: AHR CHD3 ENO1 KLHL20 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM
Entrez ID		54904	10625
HPRD ID		06155	10004
Ensembl ID		ENSG00000147548	ENSG00000116679
Uniprot IDs		Q9BZ95	Q9Y6Y0
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR 7JYN	5YY8 6N34 6N3H
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Replicative Senescence Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process PML Body Euchromatin Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Negative Regulation Of Biosynthetic Process Regulation Of Programmed Cell Death Negative Regulation Of Transcription By RNA Polymerase II Protein K63-linked Ubiquitination Apoptotic Signaling Pathway Regulation Of Intracellular Signal Transduction Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Protein Localization To Nucleus Cell Differentiation Chromosome, Telomeric Region Cellular Developmental Process Chromatin Remodeling DNA-binding Transcription Factor Activity Pexophagy Negative Regulation Of B Cell Proliferation	Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Nucleus RNA Binding Regulation Of Macromolecule Metabolic Process Cytosolic Aryl Hydrocarbon Receptor Complex Type II Interferon Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Aryl Hydrocarbon Receptor Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Cellular Response To Type II Interferon Protein K33-linked Ubiquitination Phagocytic Vesicle Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Termination Of RNA Polymerase I Transcription Histone H3K27 Trimethyltransferase Activity Response To Type II Interferon
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