GLYR1 and GEMIN4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GLYR1	GEMIN4
Gene Name		glyoxylate reductase 1 homolog (Arabidopsis)	gem (nuclear organelle) associated protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Gemini Of Coiled Bodies
	Molecular Function	DNA Binding Phosphogluconate Dehydrogenase (decarboxylating) Activity Methylated Histone Binding NAD Binding	Protein Binding
	Biological Process	Pentose-phosphate Shunt	Spliceosomal SnRNP Assembly RRNA Processing Gene Expression NcRNA Metabolic Process
Pathways			snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		8 interactors: C6orf165 CCNC EIF1AD FHL2 GEMIN4 HIST3H3 KDM1A WHSC1L1	25 interactors: AGO2 CALCOCO2 DDX20 DHX9 DMPK FLAD1 GEMIN5 GLYR1 KARS LGALS1 LGALS3 MORC4 PIAS3 RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD1 SNRPD2 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TOP1
Entrez ID		84656	50628
HPRD ID		17625	07370
Ensembl ID		ENSG00000140632	ENSG00000179409
Uniprot IDs		Q49A26	I3L2C7 P57678 Q8WUM5
PDB IDs		2UYY 4GUR 4GUS 4GUT 4GUU 4HSU
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Primitive Erythrocyte Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Atrial Cardiac Muscle Cell Development Nitrogen Compound Metabolic Process Muscle Cell Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Transcription, DNA-templated Chromosome Organization Histone H3-K27 Methylation Cellular Metabolic Process RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Megakaryocyte Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Hormone Biosynthetic Process Muscle Cell Differentiation Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Heart Trabecula Formation Granulocyte Differentiation Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Histone Modification Regulation Of Megakaryocyte Differentiation Ventricular Cardiac Muscle Cell Development Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Gene Expression Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Heart Trabecula Morphogenesis	Spliceosomal SnRNP Assembly RNA Processing MRNA Processing NcRNA Metabolic Process Ribonucleoprotein Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Biogenesis Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Neutrophil Degranulation RNA Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Activation Involved In Immune Response Gene Expression Immune Response Cellular Component Assembly Neutrophil Mediated Immunity Production Of MiRNAs Involved In Gene Silencing By MiRNA Neutrophil Activation Immune System Process Leukocyte Activation Involved In Immune Response Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Leukocyte Degranulation Lysyl-tRNA Aminoacylation Negative Regulation Of Immunological Synapse Formation FAD Biosynthetic Process Positive Regulation Of Erythrocyte Aggregation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Spliceosomal Complex Assembly Gene Silencing By RNA Cellular Metabolic Process MRNA Cleavage Involved In Gene Silencing By MiRNA Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Diadenosine Tetraphosphate Biosynthetic Process Response To DsRNA Cellular Process Vesicle Docking Membrane Docking SiRNA Loading Onto RISC Involved In RNA Interference Positive Regulation Of Mononuclear Cell Migration Mononuclear Cell Migration
Tagcloud ?		catalytic catalyzed characterization characterize cofactor crystal define demethylases demethylation determinants dodecapeptide dynamic epigenetic establish eukaryotic fundamental h3k4 h3k4me1 h3k4me2 intrinsic kdm1b linker lsd2 minimal npac represents resolutions stimulates stimulating	a1 a11 a2 a4 a5 a6 accomplishments annealing annexin annexins carbohydrate conjunction cytoplasm cytoskeleton extensively galectin galectins helicase inside interacting lectin lectins outside phospholipid possesses primer summarizes synexin unwinding
Tagcloud (Difference) ?		catalytic catalyzed characterization characterize cofactor crystal define demethylases demethylation determinants dodecapeptide dynamic epigenetic establish eukaryotic fundamental h3k4 h3k4me1 h3k4me2 intrinsic kdm1b linker lsd2 minimal npac represents resolutions stimulates stimulating	a1 a11 a2 a4 a5 a6 accomplishments annealing annexin annexins carbohydrate conjunction cytoplasm cytoskeleton extensively galectin galectins helicase inside interacting lectin lectins outside phospholipid possesses primer summarizes synexin unwinding
Tagcloud (Intersection) ?