RECK and TRIM69

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RECK	TRIM69
Gene Name		reversion-inducing-cysteine-rich protein with kazal motifs	tripartite motif containing 69
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Anchored Component Of Membrane	Nucleus Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Blood Vessel Maturation Embryo Implantation Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization	Apoptotic Process Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)
Protein-Protein Interactions		12 interactors: CTH KEAP1 KRT40 MEOX2 MMP9 NOTCH2NL REL TCF4 TEKT4 TRIM39 TRIM69 USHBP1	22 interactors: APP ASNS ATP5G1 DVL1 FAM110A FKBP1B HAUS1 IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 ZNF483
Entrez ID		8434	140691
HPRD ID		05567	11518
Ensembl ID		ENSG00000122707	ENSG00000185880
Uniprot IDs		A8K9D8 O95980	Q86WT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Binding Protein Sulfhydration Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Protein-pyridoxal-5-phosphate Linkage Transsulfuration Catenin Import Into Nucleus Embryo Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Binding Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Signal Transduction Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Receptor Binding Maintenance Of DNA Repeat Elements Cysteine Biosynthetic Process Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Protein Binding Protein Modification By Small Protein Conjugation Positive Regulation Of Cell Death Positive Regulation Of Keratinocyte Migration Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Somite Specification Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Embryonic Genitalia Morphogenesis Myoblast Fate Commitment Cysteine Metabolic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Homocysteine Metabolic Process Secretory Granule Localization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Hindgut Morphogenesis Transcription From RNA Polymerase II Promoter Negative Regulation Of Apoptotic Signaling Pathway Insulin Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Binding Hindgut Development Ossification	MRNA 3'-splice Site Recognition Collateral Sprouting Maintenance Of Protein Location In Nucleus Anatomical Structure Development System Development Negative Regulation Of Catalytic Activity Protein Localization To Nucleus Regulation Of Cell Development Developmental Process Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Cell Development Morphogenesis Of An Epithelium MRNA Splice Site Selection Multicellular Organismal Development Organ Development Positive Regulation Of Neuron Projection Development Regulation Of Neuron Differentiation Neuromuscular Junction Development Cellular Nitrogen Compound Metabolic Process Epithelium Development Negative Regulation Of Translation In Response To Oxidative Stress L-asparagine Biosynthetic Process Regulation Of Hormone Levels Anatomical Structure Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Tissue Development Regulation Of Translation Spliceosomal Complex Assembly Positive Regulation Of Cell Projection Organization Tissue Morphogenesis Positive Regulation Of Cell Cycle Regulation Of Proteolysis Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Cell Differentiation Calcium Ion Homeostasis Regulation Of Neurogenesis Positive Regulation Of Protein Metabolic Process Gene Expression Cellular Component Assembly Regulation Of Calcium Ion Transport Into Cytosol Synaptic Growth At Neuromuscular Junction Positive Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Neuron Differentiation Nitrogen Compound Metabolic Process Response To Light Stimulus Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		appendicular bioengineering biomechanical bones cartilaginous chondrocyte cleaving collagenase condensation crest ecm ectoderm embryological endochondral intracellularly intramembranous look mesoderm metalloproteinases mmps multipotent originate ossification osteocyte pericellular perimeter refined remodeling timps
Tagcloud (Difference) ?		appendicular bioengineering biomechanical bones cartilaginous chondrocyte cleaving collagenase condensation crest ecm ectoderm embryological endochondral intracellularly intramembranous look mesoderm metalloproteinases mmps multipotent originate ossification osteocyte pericellular perimeter refined remodeling timps
Tagcloud (Intersection) ?