RECK and TRIM39

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RECK	TRIM39
Gene Name		reversion-inducing-cysteine-rich protein with kazal motifs	tripartite motif containing 39
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Anchored Component Of Membrane	Mitochondrion Cytosol
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity	Protein Binding Zinc Ion Binding Ligase Activity Identical Protein Binding
	Biological Process	Blood Vessel Maturation Embryo Implantation Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization	Apoptotic Process Protein Ubiquitination Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)
Protein-Protein Interactions		12 interactors: CTH KEAP1 KRT40 MEOX2 MMP9 NOTCH2NL REL TCF4 TEKT4 TRIM39 TRIM69 USHBP1	52 interactors: APP CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 KDM1A LNX1 LXN MED18 MNAT1 OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMD9 RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1 UBTD2 UBXN1 UBXN6 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26
Entrez ID		8434	56658
HPRD ID		05567	09298
Ensembl ID		ENSG00000122707	ENSG00000204599
Uniprot IDs		A8K9D8 O95980	Q9HCM9
PDB IDs			2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Binding Protein Sulfhydration Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Protein-pyridoxal-5-phosphate Linkage Transsulfuration Catenin Import Into Nucleus Embryo Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Binding Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Signal Transduction Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Receptor Binding Maintenance Of DNA Repeat Elements Cysteine Biosynthetic Process Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Protein Binding Protein Modification By Small Protein Conjugation Positive Regulation Of Cell Death Positive Regulation Of Keratinocyte Migration Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Somite Specification Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Embryonic Genitalia Morphogenesis Myoblast Fate Commitment Cysteine Metabolic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Homocysteine Metabolic Process Secretory Granule Localization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Hindgut Morphogenesis Transcription From RNA Polymerase II Promoter Negative Regulation Of Apoptotic Signaling Pathway Insulin Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Binding Hindgut Development Ossification	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Metabolic Process Regulation Of Proteolysis Regulation Of Protein Ubiquitination Protein K63-linked Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Toll-like Receptor 4 Signaling Pathway Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Toll-like Receptor Signaling Pathway Regulation Of Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Activation Of Innate Immune Response
Tagcloud ?		appendicular bioengineering biomechanical bones cartilaginous chondrocyte cleaving collagenase condensation crest ecm ectoderm embryological endochondral intracellularly intramembranous look mesoderm metalloproteinases mmps multipotent originate ossification osteocyte pericellular perimeter refined remodeling timps	293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Difference) ?		appendicular bioengineering biomechanical bones cartilaginous chondrocyte cleaving collagenase condensation crest ecm ectoderm embryological endochondral intracellularly intramembranous look mesoderm metalloproteinases mmps multipotent originate ossification osteocyte pericellular perimeter refined remodeling timps	293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Intersection) ?