THOC3 and DDX39B

Number of citations of the paper that reports this interaction (PMID 17190602)
119

Data Source:
BioGRID (affinity chromatography technology, biochemical, pull down, affinity chromatography technology)

		THOC3	DDX39B
Gene Name		THO complex 3	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex Part Of Transcription Export Complex Nucleoplasm Golgi Apparatus Nuclear Speck Intracellular Membrane-bounded Organelle	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Speck
	Molecular Function	RNA Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity U6 SnRNA Binding U4 SnRNA Binding ATP-dependent Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of DNA Damage Checkpoint
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: BRCA1 DDX39B MLKL TK1	24 interactors: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 STRN4 TDG THOC3 THOC5 THOC6 THOC7 TUBB3 YWHAG ZHX1
Entrez ID		84321	7919
HPRD ID		09497	00805
Ensembl ID		ENSG00000051596	ENSG00000198563
Uniprot IDs		Q96J01	Q13838
PDB IDs			1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Fetal Process Involved In Parturition Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Response To DNA Damage Stimulus Skeletal Muscle Cell Proliferation Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation RNA Secondary Structure Unwinding Negative Regulation Of DNA Damage Checkpoint Protein Homooligomerization Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Response To Cortisol Thymidine Metabolic Process Dosage Compensation By Inactivation Of X Chromosome Viral MRNA Export From Host Cell Nucleus Deoxyribonucleoside Monophosphate Biosynthetic Process Protein K6-linked Ubiquitination Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Regulation Of Centriole Replication Regulation Of DNA Damage Checkpoint Positive Regulation Of Histone H3-K4 Methylation Protein Oligomerization Cellular Component Assembly Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Cell Cycle DNA Damage Response, Signal Transduction Resulting In Transcription Response To Steroid Hormone Regulation Of Cell Cycle Process Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Parturition Protein Homotrimerization Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Postreplication Repair Positive Regulation Of Protein Acetylation	MRNA Export From Nucleus RNA Export From Nucleus Viral MRNA Export From Host Cell Nucleus MRNA Metabolic Process Nuclear Export MRNA Transport RNA Transport RNA Localization MRNA Processing RNA Splicing Intracellular Transport Of Virus RNA Processing Nucleocytoplasmic Transport Nuclear Transport RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Transport Viral Life Cycle Viral Process Intracellular Transport Establishment Of Localization In Cell Cellular Metabolic Process Cellular Localization Regulation Of RNA Export From Nucleus Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription, Elongation Nuclear-transcribed MRNA Catabolic Process Regulation Of RNA Metabolic Process MRNA Catabolic Process Termination Of RNA Polymerase II Transcription RNA Catabolic Process Regulation Of Intracellular Transport Aromatic Compound Catabolic Process Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Transport Regulation Of DNA-templated Transcription, Elongation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Metabolic Process SnRNA Export From Nucleus
Tagcloud ?			22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax
Tagcloud (Difference) ?			22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax
Tagcloud (Intersection) ?