THOC3

Gene Name		THO complex 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex Part Of Transcription Export Complex Nucleoplasm Golgi Apparatus Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: BRCA1 DDX39B MLKL TK1
Entrez ID		84321
HPRD ID		09497
Ensembl ID		ENSG00000051596
Uniprot IDs		Q96J01
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Fetal Process Involved In Parturition Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Response To DNA Damage Stimulus Skeletal Muscle Cell Proliferation Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation RNA Secondary Structure Unwinding Negative Regulation Of DNA Damage Checkpoint Protein Homooligomerization Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Response To Cortisol Thymidine Metabolic Process Dosage Compensation By Inactivation Of X Chromosome Viral MRNA Export From Host Cell Nucleus Deoxyribonucleoside Monophosphate Biosynthetic Process Protein K6-linked Ubiquitination Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Regulation Of Centriole Replication Regulation Of DNA Damage Checkpoint Positive Regulation Of Histone H3-K4 Methylation Protein Oligomerization Cellular Component Assembly Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Cell Cycle DNA Damage Response, Signal Transduction Resulting In Transcription Response To Steroid Hormone Regulation Of Cell Cycle Process Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Parturition Protein Homotrimerization Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Postreplication Repair Positive Regulation Of Protein Acetylation
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