ZMYND12 and PATL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYND12	PATL1
Description		zinc finger MYND-type containing 12	PAT1 homolog 1, processing body mRNA decay factor
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GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	P-body Nucleus Cytoplasm Cytosol PML Body Nuclear Speck CCR4-NOT Complex Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding
	Biological Process	Sperm Axoneme Assembly Flagellated Sperm Motility	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA P-body Assembly
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
Interacting Genes		80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	25 interacting genes: APP CLK2 DMRTB1 FHL3 GOLGA2 KRT31 KRTAP6-2 LSM2 LSM6 MIR1-2 MIR138-2 MIR15B MIR19B1 MIR19B2 MIR20B MIR21 MIR25 MIR29B2 NFKBID PSMA3 RBPMS SNCA TSC1 WWOX ZMYND12
Entrez ID		84217	219988
HPRD ID		15740	08214
Ensembl ID		ENSG00000066185	ENSG00000166889
Uniprot IDs		B4DX70 Q9H0C1	Q86TB9
PDB IDs		8J07	2XEQ 2XER 2XES
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Extracellular Vesicle Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Lsm2-8 Complex MiRNA-mediated Gene Silencing By Inhibition Of Translation U6 SnRNP Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Vascular Endothelial Growth Factor Production Adult Locomotory Behavior Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Tetramerization Regulation Of Inflammatory Response Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Neurotransmitter Uptake P-body Negative Regulation Of Smooth Muscle Cell Differentiation Regulation Of Non-canonical NF-kappaB Signal Transduction Cellular Response To Copper Ion Negative Regulation Of Autophagy Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of T-helper Cell Differentiation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport
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