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PATL1
Description
PAT1 homolog 1, processing body mRNA decay factor
Image
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Cytosol
PML Body
Nuclear Speck
CCR4-NOT Complex
Cytoplasmic Ribonucleoprotein Granule
Molecular Function
RNA Binding
Protein Binding
Poly(U) RNA Binding
Poly(G) Binding
Biological Process
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
P-body Assembly
Pathways
mRNA decay by 5' to 3' exoribonuclease
mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
SELENOH
Interacting Genes
25 interacting genes:
APP
CLK2
DMRTB1
FHL3
GOLGA2
KRT31
KRTAP6-2
LSM2
LSM6
MIR1-2
MIR138-2
MIR15B
MIR19B1
MIR19B2
MIR20B
MIR21
MIR25
MIR29B2
NFKBID
PSMA3
RBPMS
SNCA
TSC1
WWOX
ZMYND12
Entrez ID
219988
HPRD ID
08214
Ensembl ID
ENSG00000166889
Uniprot IDs
Q86TB9
PDB IDs
2XEQ
2XER
2XES
Enriched GO Terms of Interacting Partners
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RISC Complex
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA Base-pairing Post-transcriptional Repressor Activity
Negative Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Extracellular Vesicle
Regulation Of Gene Expression
Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Vascular Endothelial Cell Proliferation
Negative Regulation Of Macromolecule Metabolic Process
MRNA 3'-UTR Binding
Lsm2-8 Complex
MiRNA-mediated Gene Silencing By Inhibition Of Translation
U6 SnRNP
Negative Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of T-helper 17 Cell Differentiation
Negative Regulation Of Vascular Endothelial Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Negative Regulation Of Endothelial Cell Migration
Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Vascular Endothelial Growth Factor Production
Adult Locomotory Behavior
Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Protein Tetramerization
Regulation Of Inflammatory Response
Positive Regulation Of T-helper 17 Type Immune Response
Regulation Of Neurotransmitter Uptake
P-body
Negative Regulation Of Smooth Muscle Cell Differentiation
Regulation Of Non-canonical NF-kappaB Signal Transduction
Cellular Response To Copper Ion
Negative Regulation Of Autophagy
Regulation Of Presynapse Organization
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Presynapse Assembly
Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Positive Regulation Of T-helper Cell Differentiation
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Calcium Ion Transmembrane Transport
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