PATL1 and MIR29B2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		PATL1	MIR29B2
Description		PAT1 homolog 1, processing body mRNA decay factor	microRNA 29b-2
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol PML Body Nuclear Speck CCR4-NOT Complex Cytoplasmic Ribonucleoprotein Granule	RISC Complex
	Molecular Function	RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA P-body Assembly	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS			Schizophrenia ( 30285260)
Interacting Genes		25 interacting genes: APP CLK2 DMRTB1 FHL3 GOLGA2 KRT31 KRTAP6-2 LSM2 LSM6 MIR1-2 MIR138-2 MIR15B MIR19B1 MIR19B2 MIR20B MIR21 MIR25 MIR29B2 NFKBID PSMA3 RBPMS SNCA TSC1 WWOX ZMYND12	70 interacting genes: ADARB1 C1QBP CELF1 DARS1 DDX1 DDX21 DDX3X EIF2AK2 EPRS1 ERAL1 FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PATL1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 QARS1 RARS1 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		219988	407025
HPRD ID		08214
Ensembl ID		ENSG00000166889	ENSG00000284203
Uniprot IDs		Q86TB9
PDB IDs		2XEQ 2XER 2XES
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Extracellular Vesicle Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Lsm2-8 Complex MiRNA-mediated Gene Silencing By Inhibition Of Translation U6 SnRNP Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Vascular Endothelial Growth Factor Production Adult Locomotory Behavior Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Tetramerization Regulation Of Inflammatory Response Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Neurotransmitter Uptake P-body Negative Regulation Of Smooth Muscle Cell Differentiation Regulation Of Non-canonical NF-kappaB Signal Transduction Cellular Response To Copper Ion Negative Regulation Of Autophagy Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of T-helper Cell Differentiation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Nucleus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Macromolecule Metabolic Process Spliceosomal Complex Catalytic Step 2 Spliceosome Nucleoplasm Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA 3'-UTR Binding Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex MiRNA Binding Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process MRNA Stabilization Nucleolus Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Gene Expression RNA Stabilization Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process CRD-mediated MRNA Stabilization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Pre-mRNA Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?