ZMYND12 and SMG9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYND12	SMG9
Description		zinc finger MYND-type containing 12	SMG9 nonsense mediated mRNA decay factor
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GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Sperm Axoneme Assembly Flagellated Sperm Motility	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Eye Development In Utero Embryonic Development Brain Development Heart Development Negative Regulation Of Apoptotic Process
Pathways			Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Lymphocyte count ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010)
Interacting Genes		80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	39 interacting genes: AGTRAP AK8 ARFIP2 CCDC57 CEP76 CMTM4 CTAG1A CTAG1B DGAT2L6 FNTB GOLGA2 GSG1 HSF2BP INCA1 KRT31 KRT34 KRTAP10-8 MTUS2 NFKBID PFDN5 PHF1 PLEKHG4 PNMA3 PPP2R3C PRKAR1B RASSF10 REL SLC17A9 SLC50A1 SYP TCF4 TRAF2 TRIM23 TRIM27 TRIP6 TSC1 TTC19 ZMYND12 ZNF655
Entrez ID		84217	56006
HPRD ID		15740	07800
Ensembl ID		ENSG00000066185	ENSG00000105771
Uniprot IDs		B4DX70 Q9H0C1	Q9H0W8
PDB IDs		8J07	6L54 6SYT 6Z3R 7PW4 7PW5 7PW7 7PW8 7PW9 8FE7
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity	Protein Binding Identical Protein Binding
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