ZMYND12 and UNC5CL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYND12	UNC5CL
Description		zinc finger MYND-type containing 12	unc-5 family C-terminal like
Image			No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	Cytoplasm Centrosome Cytosol Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Netrin Receptor Activity Protein Binding Peptidase Activity
	Biological Process	Sperm Axoneme Assembly Flagellated Sperm Motility	Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease or family history of Alzheimer's disease ( 33589840) Esophageal cancer ( 21642993) Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866) Urate levels ( 31578528)
Interacting Genes		80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	7 interacting genes: KRTAP13-2 KRTAP6-1 NFKB1 PGAM1 RELA TOX2 ZMYND12
Entrez ID		84217	222643
HPRD ID		15740	09844
Ensembl ID		ENSG00000066185	ENSG00000124602
Uniprot IDs		B4DX70 Q9H0C1	H8YHX0 Q8IV45
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity	NF-kappaB P50/p65 Complex Cellular Response To Nicotine Cellular Response To Angiotensin Actinin Binding Cellular Response To Interleukin-6 Response To Interleukin-6 Response To Muscle Stretch Response To Angiotensin Non-canonical NF-kappaB Signal Transduction Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Cytokine Production Involved In Inflammatory Response Response To Nicotine Transcription Coactivator Binding Tumor Necrosis Factor-mediated Signaling Pathway Canonical NF-kappaB Signal Transduction Positive Regulation Of MiRNA Metabolic Process Regulation Of Interleukin-12 Production Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of MiRNA Metabolic Process Chromatin DNA Binding Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Positive Regulation Of Hyaluronan Biosynthetic Process Secretory Granule Lumen I-kappaB/NF-kappaB Complex Phosphoglycerate Mutase Activity Bisphosphoglycerate Mutase Activity Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin Negative Regulation Of Vitamin D Biosynthetic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Intermediate Filament Mammary Gland Involution Postsynapse To Nucleus Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Response To Mechanical Stimulus Regulation Of Hyaluronan Biosynthetic Process Ankyrin Repeat Binding Cellular Response To Peptidoglycan Cellular Response To Interleukin-17 Intramolecular Phosphotransferase Activity Transcription Regulator Complex Regulation Of Vitamin Metabolic Process Defense Response To Tumor Cell Negative Regulation Of Protein Sumoylation
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