ZMYND12 and PRR5L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYND12	PRR5L
Description		zinc finger MYND-type containing 12	proline rich 5 like
Image			No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	TORC2 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Sperm Axoneme Assembly Flagellated Sperm Motility	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Fibroblast Migration Cellular Response To Oxidative Stress TORC2 Signaling Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS			A body shape index ( 34021172) Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 32296059 31619474 31361310 30929738) Asthma (childhood onset) ( 30929738) Atopic dermatitis ( 23727859 26482879) Hip index ( 34021172) Idiopathic inflammatory myopathy ( 26362759) Inflammatory skin disease ( 25574825) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Photic sneeze reflex ( 27182965) Red blood cell count ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	15 interacting genes: CCDC91 EFHC1 FHL2 FHL3 HSF2BP KANK2 MAD2L2 MISP MLH1 MORN3 MTOR PHAF1 SCNM1 USP2 ZMYND12
Entrez ID		84217	79899
HPRD ID		15740	07854
Ensembl ID		ENSG00000066185	ENSG00000135362
Uniprot IDs		B4DX70 Q9H0C1	B3KNU3 Q6MZQ0
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity	Negative Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Calcium-mediated Signaling Regulation Of Signal Transduction By P53 Class Mediator Cardiac Cell Development Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Cardiac Muscle Cell Development Organelle Organization Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response Double-strand Break Repair Male Meiotic Nuclear Division Negative Regulation Of DNA Recombination Positive Regulation Of Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Late Recombination Nodule Somatic Diversification Of Immunoglobulins Meiotic Metaphase I Homologous Chromosome Alignment DNA Damage Response, Signal Transduction Resulting In Transcription Cytoskeleton Organization Positive Regulation Of Immunoglobulin Production Atrial Cardiac Muscle Cell Development Regulation Of Locomotor Rhythm TFIIIC-class Transcription Factor Complex Binding Meiotic Spindle Midzone Assembly Meiosis I Cell Cycle Process Meiotic Metaphase Chromosome Alignment Chiasma Negative Regulation Of Vitamin D Receptor Signaling Pathway Striated Muscle Cell Development Meiotic Nuclear Division Positive Regulation Of DNA Recombination
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