ZMYND12 and VPS37C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYND12	VPS37C
Description		zinc finger MYND-type containing 12	VPS37C subunit of ESCRT-I
Image			No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	ESCRT I Complex Nucleoplasm Endosome Golgi Apparatus Cilium Endosome Membrane Membrane Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Sperm Axoneme Assembly Flagellated Sperm Motility	Protein Targeting To Membrane Protein Targeting To Vacuole Protein Transport Macroautophagy Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS			Periventricular white matter hyperintensities ( 32517579) Rheumatoid arthritis ( 23143596)
Interacting Genes		80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	102 interacting genes: AARD ABHD11 ABI2 APP ASCL3 BAG4 BIRC7 C1orf94 CBFA2T3 CEP55 CRX DAZAP2 DCTN3 DDIT3 DYDC1 EYA2 FAM168A FAM168B FCHSD2 FOXI1 FUBP1 GOLGA2 GPS2 GRB2 HAUS1 HELT HGS HNRNPF HNRNPUL1 HYI ILF3 KLF1 KRT27 KRT33B KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP7-1 LAGE3 LASP1 MAPK1IP1L METTL27 NTAQ1 NUP54 NUTM2F P4HA3 PAX9 PDCD6 PDCD6IP PEF1 PKNOX1 PKNOX2 PLA2G10 PLEKHG4 PLSCR1 POLR2J POLR2J3 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 RAMAC RBPMS RBPMS2 RFX6 RIBC1 RINT1 RPRD1B RUNX1 SH3GL1 SH3RF1 SH3RF2 SORBS2 SORBS3 SPAG8 STAM2 STH TACC3 TFAP2D TFG TFIP11 TIAL1 TLE5 TSC1 TSG101 UBAP2 UBC UFSP1 VPS28 WWOX WWP2 XIAP YTHDF1 ZMAT5 ZMYND12 ZNF34
Entrez ID		84217	55048
HPRD ID		15740	15652
Ensembl ID		ENSG00000066185	ENSG00000167987
Uniprot IDs		B4DX70 Q9H0C1	A5D8V6
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity	Protein Binding Intermediate Filament Multivesicular Body Organization Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Ubiquitin-dependent Endocytosis Regulation Of Primary Metabolic Process Late Endosome To Vacuole Transport Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Exosomal Secretion Endosome Transport Via Multivesicular Body Sorting Pathway ESCRT-0 Complex Positive Regulation Of RNA Metabolic Process Endosome Organization Membrane Fission Regulation Of Protein Ubiquitination Regulation Of Exosomal Secretion Multivesicular Body Sorting Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of JNK Cascade Cytoplasmic Stress Granule Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Viral Budding Via Host ESCRT Complex Protein Serine/threonine Kinase Binding COPII Vesicle Coating Positive Regulation Of Protein Monoubiquitination Positive Regulation Of JNK Cascade Ubiquitin Binding Positive Regulation Of Transcription By RNA Polymerase II Macroautophagy Nucleus Viral Budding Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Extracellular Exosome Assembly Regulation Of Protein Monoubiquitination Positive Regulation Of Supramolecular Fiber Organization Establishment Of Protein Localization To Vacuole Vesicle Organization Transcription Regulator Complex Regulation Of Post-translational Protein Modification Cytosol Endoplasmic Reticulum Exit Site Protein Dimerization Activity Positive Regulation Of Macromolecule Biosynthetic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
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