CEP72 and SPATA2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		CEP72	SPATA2
Gene Name		centrosomal protein 72kDa	spermatogenesis associated 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol	Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Molecular_function
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spindle Organization Gamma-tubulin Complex Localization	Multicellular Organismal Development Spermatogenesis Cell Differentiation
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Ulcerative colitis ( 20228799)	Psoriasis ( 20953189 18364390)
Protein-Protein Interactions		17 interactors: ATXN7 CATIP FAM90A1 IGHM KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417	9 interactors: APP CEP72 DUT GOLGA2 LZTS2 MAD1L1 PTPN6 TRAF2 TRIM27
Entrez ID		55722	9825
HPRD ID		07685	09636
Ensembl ID		ENSG00000112877	ENSG00000158480
Uniprot IDs		Q9P209	A8K0S9 B4DID4 Q9UM82
PDB IDs
Enriched GO Terms of Interacting Partners?		Intraciliary Transport Cilium Organization Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	Mitotic Cell Cycle Regulation Of Cellular Localization Regulation Of Protein Binding Regulation Of Adaptive Immune Response Regulation Of Mitotic Cell Cycle Phase Transition Cell Cycle Regulation Of Cell Cycle Phase Transition Protein K63-linked Ubiquitination Protein Trimerization Negative Regulation Of Adaptive Immune Response Regulation Of Protein Kinase Activity Regulation Of Binding Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Innate Immune Response Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Cell Cycle DUMP Biosynthetic Process Regulation Of Metaphase Plate Congression DUTP Catabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Process Abortive Mitotic Cell Cycle Negative Regulation Of Interleukin-2 Secretion Gamma-tubulin Complex Localization Synaptic Growth At Neuromuscular Junction Immune Response Regulation Of Phosphorylation Defense Response Spindle Organization Negative Regulation Of Immune Response DUMP Metabolic Process Collateral Sprouting In Absence Of Injury DUTP Metabolic Process Positive Regulation Of Peptidase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Protein Polyubiquitination Negative Regulation Of B Cell Receptor Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Regulation Of Calcium Ion Transport Platelet Activation Microtubule-based Process
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