ZFYVE16

Description		zinc finger FYVE-type containing 16
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GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Membrane Early Endosome Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis
Pathways		Signaling by BMP
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Psoriasis ( 25854761)
Novel Interacting Genes		1 novel interacting genes: MEF2C
Interacting Genes		6 interacting genes: APP EEA1 PPP1CA RNF11 TOM1 UBC
Entrez ID		9765
HPRD ID		10319
Ensembl ID		ENSG00000039319
Uniprot IDs		Q7Z3T8
PDB IDs		3T7L 5MK0
Enriched GO Terms of Interacting Partners?		NMDA Selective Glutamate Receptor Signaling Pathway Early Endosome Response To Lead Ion Recycling Endosome Transition Metal Ion Binding Extracellular Exosome Early Endosome Membrane Ionotropic Glutamate Receptor Signaling Pathway Postsynapse Positive Regulation Of Protein-containing Complex Disassembly Endosome Ligand-gated Ion Channel Signaling Pathway Glutamate Receptor Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Metal Ion Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Sinoatrial Valve Morphogenesis Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Apoptotic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Programmed Cell Death Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Neuron Differentiation Growth Cone Filopodium Endocytosis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Macrophage Apoptotic Process Primary Heart Field Specification Muscle Cell Fate Determination Glomerulus Morphogenesis Nephron Tubule Epithelial Cell Differentiation Cellular Response To Trichostatin A RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of Protein-containing Complex Disassembly Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Vesicle Fusion Organelle Membrane Fusion
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