BRF1 and GTF3C5

Number of citations of the paper that reports this interaction (PMID 10373544)
23

Data Source:
HPRD (in vitro)

		BRF1	GTF3C5
Gene Name		BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	general transcription factor IIIC, polypeptide 5, 63kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIB Complex Nucleoplasm	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	Zinc Ion Binding TBP-class Protein Binding	DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Gene Expression Regulation Of MRNA Stability	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419)
Protein-Protein Interactions		13 interactors: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 TBP TP53	12 interactors: BRF1 GTF3C3 GTF3C4 GTF3C6 KRT40 KRTAP10-3 MDFI NOTCH2NL SRA1 TBP TCF21 TCF4
Entrez ID		2972	9328
HPRD ID		05361	16077
Ensembl ID		ENSG00000185024	ENSG00000148308
Uniprot IDs		Q92994	H9KV68 Q9Y5Q8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase III Promoter RRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter TRNA Transcription Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Macromolecule Biosynthetic Process Neuron Apoptotic Process Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Neuron Death Positive Regulation Of Gene Expression Regulation Of Cell Cycle Phase Transition Glial Cell Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Chromatin Organization Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Checkpoint Regulation Of RNA Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of Metabolic Process Neuron Maturation Chromosome Organization Regulation Of Chromosome Organization Viral Process Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation	TRNA Transcription Transcription From RNA Polymerase III Promoter RRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Transcription, DNA-templated RNA Biosynthetic Process DNA-templated Transcription, Initiation RNA Metabolic Process Transcription Initiation From RNA Polymerase III Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Organ Development Reproductive Structure Development Reproductive System Development Embryonic Digestive Tract Morphogenesis Nucleobase-containing Compound Metabolic Process Single Organism Reproductive Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Embryonic Morphogenesis Reproductive Process Cellular Nitrogen Compound Metabolic Process Embryonic Digestive Tract Development Developmental Process Involved In Reproduction Nitrogen Compound Metabolic Process Embryonic Organ Morphogenesis Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Embryo Development Multicellular Organism Growth Embryonic Placenta Development Cell Differentiation Blood Vessel Development Vasculature Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Proepicardium Development Negative Regulation Of Gene Expression Digestive Tract Development Negative Regulation Of Biosynthetic Process Maintenance Of DNA Repeat Elements Bronchiole Development Digestive System Development
Tagcloud ?		5s alcohol cjun colony consumption decreases deregulation downregulate enhances eralpha iii indicates inhibits jun occupancy pol promoters reduces repress repressing repression rrna tam tamoxifen transcription translational trnas uncover upregulate	acetylated allowing architecture became branching chipseq coordinated depolarization depolarizing discovered dramatic factories interplay interspersed mimicked nee rearrangement relies relocated relocation remarkably silencing sines somatosensory synaptic tfiiic tfs timely uncontrolled
Tagcloud (Difference) ?		5s alcohol cjun colony consumption decreases deregulation downregulate enhances eralpha iii indicates inhibits jun occupancy pol promoters reduces repress repressing repression rrna tam tamoxifen transcription translational trnas uncover upregulate	acetylated allowing architecture became branching chipseq coordinated depolarization depolarizing discovered dramatic factories interplay interspersed mimicked nee rearrangement relies relocated relocation remarkably silencing sines somatosensory synaptic tfiiic tfs timely uncontrolled
Tagcloud (Intersection) ?