BRF1 and GTF3C3

Number of citations of the paper that reports this interaction (PMID 10373544)
23

Data Source:
HPRD (in vivo, in vitro)

		BRF1	GTF3C3
Gene Name		BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	general transcription factor IIIC, polypeptide 3, 102kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIB Complex Nucleoplasm	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	Zinc Ion Binding TBP-class Protein Binding	DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Gene Expression Regulation Of MRNA Stability	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419)
Protein-Protein Interactions		13 interactors: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 TBP TP53	7 interactors: BRF1 DEDD DEDD2 GTF3C5 HNRNPD PCBD1 TBP
Entrez ID		2972	9330
HPRD ID		05361	11997
Ensembl ID		ENSG00000185024	ENSG00000119041
Uniprot IDs		Q92994	Q9Y5Q9
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase III Promoter RRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter TRNA Transcription Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Macromolecule Biosynthetic Process Neuron Apoptotic Process Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Neuron Death Positive Regulation Of Gene Expression Regulation Of Cell Cycle Phase Transition Glial Cell Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Chromatin Organization Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Checkpoint Regulation Of RNA Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of Metabolic Process Neuron Maturation Chromosome Organization Regulation Of Chromosome Organization Viral Process Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase III Promoter RNA Metabolic Process TRNA Transcription Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Aromatic Compound Catabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Catabolic Process Biosynthetic Process RRNA Transcription Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Extrinsic Apoptotic Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Proepicardium Development Catabolic Process Placenta Development Cellular Macromolecule Catabolic Process 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Circadian Regulation Of Translation DNA-templated Transcription, Initiation Apoptotic Process Programmed Cell Death Transcription Initiation From RNA Polymerase III Promoter Cell Death Death Tetrahydrobiopterin Biosynthetic Process Cellular Metabolic Process Regulation Of Translation Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RRNA Catabolic Process L-phenylalanine Catabolic Process
Tagcloud ?		5s alcohol cjun colony consumption decreases deregulation downregulate enhances eralpha iii indicates inhibits jun occupancy pol promoters reduces repress repressing repression rrna tam tamoxifen transcription translational trnas uncover upregulate
Tagcloud (Difference) ?		5s alcohol cjun colony consumption decreases deregulation downregulate enhances eralpha iii indicates inhibits jun occupancy pol promoters reduces repress repressing repression rrna tam tamoxifen transcription translational trnas uncover upregulate
Tagcloud (Intersection) ?