PGRMC1 and CAMLG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PGRMC1	CAMLG
Description		progesterone receptor membrane component 1	calcium modulating ligand
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GO Annotations	Cellular Component	Extracellular Region Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Lipid Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Heme Biosynthetic Process Axon Guidance Memory Associative Learning Modification Of Synaptic Structure Positive Regulation Of Lipoprotein Transport Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Synapse Organization	B Cell Homeostasis Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Neutrophil degranulation	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Dextromethorphan Nortriptyline Sertraline	Cyclosporine Voclosporin
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)	Height ( 18391951)
Interacting Genes		20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 LINC00632 MTNR1A PAM16 SCAP SGTB TMEM213 ZNF71	21 interacting genes: ADIPOQ AGR2 BCL2L13 EGFR ETNK1 F11R GET1 HSP90B1 HSPA13 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		10857	819
HPRD ID		02338	03073
Ensembl ID		ENSG00000101856	ENSG00000164615
Uniprot IDs		O00264 Q6IB11	P49069
PDB IDs		4X8Y	6SO5 8CR1
Enriched GO Terms of Interacting Partners?		GET Complex	Endoplasmic Reticulum Localization Within Membrane Positive Regulation Of Protein Localization To Plasma Membrane Endoplasmic Reticulum Chaperone Complex Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Membrane Protein Localization To Cell Periphery Digestive Tract Morphogenesis Protein-containing Complex Smooth Endoplasmic Reticulum Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Protein Localization To Membrane
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