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PGRMC1

Description progesterone receptor membrane component 1
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Endoplasmic Reticulum
  • Plasma Membrane
  • Endomembrane System
  • Membrane
  • Smooth Endoplasmic Reticulum Membrane
  • Specific Granule Membrane
  • Neuron Projection
  • Neuronal Cell Body
  • Cell Body
  • Synapse
Molecular Function
  • Amyloid-beta Binding
  • Steroid Binding
  • Protein Binding
  • Lipid Binding
  • Heme Binding
  • Protein Homodimerization Activity
  • Metal Ion Binding
Biological Process
  • Heme Biosynthetic Process
  • Axon Guidance
  • Memory
  • Associative Learning
  • Modification Of Synaptic Structure
  • Positive Regulation Of Lipoprotein Transport
  • Positive Regulation Of Protein Localization To Plasma Membrane
  • Negative Regulation Of Synapse Organization
Pathways
  • Neutrophil degranulation
Drugs
  • Dextromethorphan
  • Nortriptyline
  • Sertraline
Diseases
GWAS
  • Hodgkin's lymphoma ( 34216518)
Novel Interacting Genes 1 novel interacting genes: MX1
Interacting Genes 20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 LINC00632 MTNR1A PAM16 SCAP SGTB TMEM213 ZNF71
Entrez ID 10857
HPRD ID 02338
Ensembl ID ENSG00000101856
Uniprot IDs O00264 Q6IB11
PDB IDs 4X8Y
Enriched GO Terms of Interacting Partners?
  • GET Complex
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© Madhavi K. Ganapathiraju 2012-2025