ELL and HNRNPU

Number of citations of the paper that reports this interaction (PMID 10490622)
12

Data Source:
HPRD (in vivo)

		ELL	HNRNPU
Gene Name		elongation factor RNA polymerase II	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Speck Transcriptionally Active Chromatin Histone Locus Body	Nucleus Nucleoplasm Cell Surface Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Phosphatase Binding	Core Promoter Binding DNA Binding RNA Binding Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Negative Regulation Of Phosphatase Activity Viral Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Viral Transcription	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Gene Expression Circadian Regulation Of Gene Expression CRD-mediated MRNA Stabilization
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Protein-Protein Interactions		10 interactors: EAF1 EAF2 HNRNPU MCM2 POLR2A SNF8 TFPT TP53 UBC ZHX1	35 interactors: ACTB BTRC CASP3 CD5 CDKN2A CR2 ELL EP300 ERG GAS7 GRIN1 GRIN2D GTF2H1 HNRNPD HNRNPH3 IL7R KAT2B NDN NDRG1 NEDD4 NR3C1 PIN1 POLR2A POU3F4 PRMT1 PRPF40A PTPN11 SMN1 SREK1 STAU1 SYK TCERG1 WBP4 YAP1 ZNF689
Entrez ID		8178	3192
HPRD ID		02615	04185
Ensembl ID		ENSG00000105656	ENSG00000153187
Uniprot IDs		P55199	Q00839 Q96BA7
PDB IDs		2DOA	1ZRJ
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Response To DNA Damage Stimulus DNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Circadian Rhythm Regulation Of RNA Metabolic Process DNA Repair Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Rhythmic Process Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Transcription From RNA Polymerase II Promoter Apoptotic Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription From RNA Polymerase II Promoter Programmed Cell Death Cell Death Death Signal Transduction In Response To DNA Damage Nucleotide-excision Repair Mitotic DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Mitotic DNA Integrity Checkpoint	RNA Metabolic Process Developmental Process Gene Expression Regulation Of Cell Cycle Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process MRNA Processing Multicellular Organismal Development Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process RNA Splicing Positive Regulation Of Viral Transcription Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process System Development MRNA Metabolic Process Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Cellular Metabolic Process Signal Transduction RNA Processing Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Regulation Of Cellular Process RNA Biosynthetic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Anatomical Structure Morphogenesis Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Regulation Of T Cell Activation Signaling Transcription Initiation From RNA Polymerase II Promoter Cell Communication Regulation Of Metabolic Process Cellular Metabolic Process N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process
Tagcloud ?		1st backgrounds behaviors concepts confused constructs contexts distinguishable ells english examines examining language learners mothers native pathologizing ratings ses shy shyness socially socioeconomic speakers speaking unsociability unsociable withdrawal withdrawn	17p13 1q21 1q44 2q23 2q31 agilent annotations asd autism backgrounds cgh cnv cnvs disabilities dissect encephalopathy epileptic exome expand hallux implicates infantile intellectual lissencephaly mbd5 microcephaly pafah1b1 pathogenicity spasms
Tagcloud (Difference) ?		1st behaviors concepts confused constructs contexts distinguishable ells english examines examining language learners mothers native pathologizing ratings ses shy shyness socially socioeconomic speakers speaking unsociability unsociable withdrawal withdrawn	17p13 1q21 1q44 2q23 2q31 agilent annotations asd autism cgh cnv cnvs disabilities dissect encephalopathy epileptic exome expand hallux implicates infantile intellectual lissencephaly mbd5 microcephaly pafah1b1 pathogenicity spasms
Tagcloud (Intersection) ?		backgrounds