CALU and APCS

Number of citations of the paper that reports this interaction (PMID 10631319)
6

Data Source:
HPRD (in vitro)

		CALU	APCS
Gene Name		calumenin	amyloid P component, serum
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Golgi Apparatus Membrane Sarcoplasmic Reticulum Lumen Melanosome	Extracellular Region Extracellular Space Nucleus Extracellular Matrix Protein Complex Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Calcium Ion Binding Protein Binding	Complement Component C1q Binding Calcium Ion Binding Carbohydrate Binding Virion Binding Unfolded Protein Binding
	Biological Process	Platelet Degranulation Blood Coagulation Biological_process Platelet Activation	Negative Regulation Of Acute Inflammatory Response Protein Folding Acute-phase Response Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Innate Immune Response Negative Regulation Of Monocyte Differentiation Negative Regulation Of Viral Entry Into Host Cell Negative Regulation Of Viral Process Chaperone-mediated Protein Complex Assembly Negative Regulation Of Wound Healing Negative Regulation Of Exo-alpha-sialidase Activity Negative Regulation Of Glycoprotein Metabolic Process
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation	Amyloids
Drugs			Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)	C-reactive protein ( 22939635)
Protein-Protein Interactions		7 interactors: APCS CSNK2A1 CTNNAL1 PRMT5 UBQLN1 UMPS ZPBP	17 interactors: C1QA C4BPA CALU COL4A1 COPS5 CRP FCGR1A FCGR2B FCGR3A FCGR3B FN1 GK GOT2 GRB2 HES1 LAMA1 TG
Entrez ID		813	325
HPRD ID		04569	00101
Ensembl ID			ENSG00000132703
Uniprot IDs		B3KQF5 O43852 Q6IAW5	P02743
PDB IDs			1GYK 1LGN 1SAC 2A3W 2A3X 2A3Y 2W08 3D5O 3KQR 4AVS 4AVT 4AVV 4AYU
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Nuclear Division Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Negative Regulation Of Exo-alpha-sialidase Activity 'de Novo' UMP Biosynthetic Process Negative Regulation Of Monocyte Differentiation Regulation Of Cell Division 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Protein Folding Rhythmic Process Histone H4-R3 Methylation Negative Regulation Of Glycoprotein Metabolic Process Endothelial Cell Activation UMP Biosynthetic Process Chaperone-mediated Protein Complex Assembly Regulation Of Monocyte Differentiation Negative Regulation Of Acute Inflammatory Response Acrosome Assembly Negative Regulation Of Viral Entry Into Host Cell Peptidyl-arginine N-methylation Negative Regulation Of Hydrolase Activity Regulation Of Mitotic Cell Cycle Histone Arginine Methylation Regulation Of Viral Entry Into Host Cell Peptidyl-arginine Methylation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Immune System Process Immune Response Regulation Of Immune Response Regulation Of Immune System Process Positive Regulation Of Immune System Process Vesicle-mediated Transport Positive Regulation Of Immune Response Retinal Blood Vessel Morphogenesis Response To Stimulus Defense Response Phagocytosis Retina Vasculature Morphogenesis In Camera-type Eye Endocytosis Complement Activation, Classical Pathway Transport Cell Morphogenesis Involved In Differentiation Humoral Immune Response Mediated By Circulating Immunoglobulin Retina Vasculature Development In Camera-type Eye Complement Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Innate Immune Response Fc Receptor Mediated Stimulatory Signaling Pathway Blood Vessel Morphogenesis Protein Activation Cascade Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Platelet Activation Acute-phase Response Morphogenesis Of An Epithelium Blood Vessel Development Vasculature Development Generation Of Neurons Humoral Immune Response Morphogenesis Of A Branching Epithelium Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis Neurogenesis Morphogenesis Of A Branching Structure Wound Healing Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Glycerol-3-phosphate Biosynthetic Process Lateral Inhibition Labyrinthine Layer Development Leukocyte Mediated Immunity Adaptive Immune Response Fc Receptor Signaling Pathway
Tagcloud ?		abrogate abrogates atf coactivators coexpression correlate creb exert g1 g148v hela htlv immortalization interfere lymphotropic m22 m47 oligonucleotide overexpressing p53 prevents rel suppress suppression tat tax transactivation transactivator transforms	aggregates cd68 dendritic dysmaturation dysmorphic enlarged fdc fdcs follicle follicles idc idcs imply interdigitating intima ki67 kim lining lymphocyte lymphocytes pathogenetic phenomena proliferating regarded rheumatoid semiquantitative slcs synovial vicinity
Tagcloud (Difference) ?		abrogate abrogates atf coactivators coexpression correlate creb exert g1 g148v hela htlv immortalization interfere lymphotropic m22 m47 oligonucleotide overexpressing p53 prevents rel suppress suppression tat tax transactivation transactivator transforms	aggregates cd68 dendritic dysmaturation dysmorphic enlarged fdc fdcs follicle follicles idc idcs imply interdigitating intima ki67 kim lining lymphocyte lymphocytes pathogenetic phenomena proliferating regarded rheumatoid semiquantitative slcs synovial vicinity
Tagcloud (Intersection) ?