TACC2 and SMARCB1

Number of citations of the paper that reports this interaction (PMID 12620397)
8

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		TACC2	SMARCB1
Gene Name		transforming, acidic coiled-coil containing protein 2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton	Nuclear Chromatin XY Body Nucleus Nucleoplasm Nucleolus SWI/SNF Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	Protein Domain Specific Binding Nuclear Hormone Receptor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding P53 Binding Transcription Coactivator Activity Protein Binding Tat Protein Binding Nucleosomal DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Astral Microtubule Organization Regulation Of Microtubule-based Process	Blastocyst Hatching DNA Repair Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Negative Regulation Of Cell Proliferation DNA Integration Cell Differentiation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate ATP-dependent Chromatin Remodeling Positive Regulation By Host Of Viral Transcription Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661)	IgG glycosylation ( 23382691)
Protein-Protein Interactions		11 interactors: AURKC CREBBP EP300 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCB1 UBC YEATS4	40 interactors: AKT1 APP BCL2L11 CALR CDX2 CEBPB DPF2 DPF3 GADD45G GATA1 KLF1 KMT2B KMT2C MAP1LC3B MAPK8IP2 MCPH1 MECP2 MYC NONO NR0B2 NR3C1 PDPK1 PPP1CC PPP1R15A PRMT5 RAN RB1 RELB RPS6KA5 SIN3B SMARCA4 SRC TACC2 TAF1D TP53 UBQLN4 XPO1 YEATS4 ZAK ZDHHC17
Entrez ID		10579	6598
HPRD ID		05600	03364
Ensembl ID		ENSG00000138162	ENSG00000099956
Uniprot IDs		D6RAA5 E7EMZ9 E9PBC6 O95359 Q4VXL8	G5E975 Q12824 Q9H836
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Modification N-terminal Peptidyl-lysine Acetylation Chromatin Organization Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Protein Acetylation Histone Modification Positive Regulation Of Transcription, DNA-templated N-terminal Protein Amino Acid Acetylation Cell Cycle Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Peptidyl-lysine Modification Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Notch Signaling Pathway Mitotic Cell Cycle RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Chromatin Remodeling Gene Expression Regulation Of Gene Expression Peptidyl-amino Acid Modification Histone H4 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription In Response To Stress Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Type I Interferon Production Mitotic Cell Cycle Process Regulation Of Transcription, DNA-templated Positive Regulation By Host Of Viral Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process	Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Chromatin Organization Positive Regulation Of Metabolic Process Organelle Organization Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Chromatin Modification Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Chromosome Organization Regulation Of Cellular Process RNA Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Organ Development Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation System Development Regulation Of Signaling Developmental Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Negative Regulation Of Signal Transduction Regulation Of Phosphorylation Anatomical Structure Development Regulation Of Organelle Organization Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Phosphorus Metabolic Process
Tagcloud ?		abundantly affymetrix annotated ccnd1 crmp1 curing cycles ddc endpoint gabrb3 hurdle hydroxylase immunotherapy isl1 kif1a marrows mrd neuroblastoma phox2b prioritize profiling ranking sampled serves stringent surrogate top u95 uncover	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Difference) ?		abundantly affymetrix annotated ccnd1 crmp1 curing cycles ddc endpoint gabrb3 hurdle hydroxylase immunotherapy isl1 kif1a marrows mrd neuroblastoma phox2b prioritize profiling ranking sampled serves stringent surrogate top u95 uncover	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Intersection) ?