TACC2 and BORCS6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TACC2	BORCS6
Description		transforming acidic coiled-coil containing protein 2	BLOC-1 related complex subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane	Lysosome Lysosomal Membrane Membrane Cytoplasmic Side Of Lysosomal Membrane BORC Complex
	Molecular Function	Nuclear Receptor Binding	Protein Binding Identical Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Nuclear Migration Cerebral Cortex Development	Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia (time to first treatment) ( 33510140) Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)
Interacting Genes		18 interacting genes: AURKC BORCS6 CLK2 CLVS2 CREBBP EP300 FMR1 FXR1 GRAMD4 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCA2 SMARCB1 TGM1 YEATS4	31 interacting genes: ABI2 AIRIM BEX2 C19orf25 C1orf216 DRC4 EPS8 EXOC8 EXOSC5 FAM161B FAM9C FBXO44 FCHSD2 HAUS1 HGS KANK2 LNX1 MED21 MOS NDEL1 NTAQ1 OSTF1 PKNOX1 PLA2G4A RCOR3 RIBC1 SHPRH SPG21 TACC2 USHBP1 ZNF655
Entrez ID		10579	54785
HPRD ID		05600	13368
Ensembl ID		ENSG00000138162	ENSG00000196544
Uniprot IDs		B2RWP4 B7ZMJ9 D6RAA5 E7EMZ9 E9PBC6 O95359 Q4VXL4 Q4VXL8	Q96GS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Acetylation Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Acetyltransferase Activity Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Protein Acetylation Chromatin Organization Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Regulation Of DNA Repair Internal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Gluconeogenesis Transcription Coactivator Activity Acyltransferase Activity Regulation Of Cellular Response To Stress Negative Regulation Of Gluconeogenesis Histone H3K27 Acetyltransferase Activity Histone H3K9 Acetyltransferase Activity Positive Regulation Of Cell Differentiation Regulation Of Glucose Metabolic Process Positive Regulation Of Double-strand Break Repair Chromatin Remodeling Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Developmental Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Cell Development Regulation Of Multicellular Organismal Development Negative Regulation Of Small Molecule Metabolic Process Chromatin Binding Regulation Of DNA Metabolic Process RNA Strand Annealing Activity Positive Regulation Of DNA Repair Regulation Of Cell Development Protein Modification Process Regulation Of Double-strand Break Repair L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Nervous System Development Transcription Initiation-coupled Chromatin Remodeling Intracellular Membraneless Organelle Negative Regulation Of Centriole Replication Gluconeogenesis Kinetochore Positive Regulation Of Gene Expression, Epigenetic Hexose Biosynthetic Process DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process Regulation Of RNA Splicing
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