FAM192A and ATP13A2

Number of citations of the paper that reports this interaction (PMID 22645275)
9

Data Source:
BioGRID (two hybrid)

		FAM192A	ATP13A2
Gene Name		family with sequence similarity 192, member A	ATPase type 13A2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Lysosome Lysosomal Membrane Integral Component Of Membrane
	Molecular Function		Protein Binding ATP Binding ATPase Activity Metal Ion Binding
	Biological Process		Cation Transport Metabolic Process Cellular Response To Manganese Ion
Pathways
Drugs
Diseases
GWAS			Height ( 20189936)
Protein-Protein Interactions		2 interactors: ATP13A2 TRAF2	36 interactors: ACKR3 ATP5G2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM192A FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS
Entrez ID		80011	23400
HPRD ID		11389	13677
Ensembl ID		ENSG00000172775	ENSG00000159363
Uniprot IDs		Q9GZU8	Q9NQ11
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Inorganic Substance Cellular Response To Manganese Ion Response To Inorganic Substance Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Protein Homodimerization Activity Cellular Response To Nitric Oxide Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Positive Regulation Of T Cell Cytokine Production Response To Manganese Ion Protein Homotrimerization Regulation Of Protein Homodimerization Activity Cellular Response To Reactive Nitrogen Species Regulation Of T Cell Cytokine Production Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling Protein K63-linked Ubiquitination Tumor Necrosis Factor-mediated Signaling Pathway Protein Trimerization Positive Regulation Of Interleukin-2 Production NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Protein Autoubiquitination Programmed Necrotic Cell Death Necrotic Cell Death Positive Regulation Of Cytokine Production Involved In Immune Response I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of JUN Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Toll-like Receptor 4 Signaling Pathway Regulation Of JUN Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Cellular Response To Reactive Oxygen Species Cellular Response To Tumor Necrosis Factor Zymogen Activation Positive Regulation Of T Cell Mediated Immunity Toll-like Receptor Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of JNK Cascade Response To Tumor Necrosis Factor Positive Regulation Of Cysteine-type Endopeptidase Activity	Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Protein Localization To Membrane Embryonic Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Membrane Regulation Of Signaling Establishment Of Protein Localization Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Localization Membrane Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cardiovascular System Development Synaptic Transmission Motor Neuron Axon Guidance Cell-cell Signaling Locomotion Positive Regulation Of Signal Transduction Chemotaxis Face Morphogenesis Embryonic Camera-type Eye Morphogenesis ER-associated Ubiquitin-dependent Protein Catabolic Process Head Morphogenesis Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Cellular Response To Fluoride Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Tyrosine Transport Synapse Organization Protein Localization To Nucleus Embryonic Eye Morphogenesis Cellular Protein Localization Regulation Of Protein Secretion Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Homeostasis Cerebellum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Face Development Regulation Of Signal Transduction Cellular Protein Metabolic Process Regulation Of Insulin Secretion
Tagcloud ?			ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?			ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?