RBMY1J and CBX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBMY1J	CBX2
Description		RNA binding motif protein Y-linked family 1 member J	chromobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus	Euchromatin Heterochromatin Nucleus Nucleoplasm Chromosome PcG Protein Complex PRC1 Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding	DNA Binding Chromatin Binding Protein Binding Histone H3K9me2/3 Reader Activity
	Biological Process	MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Sex Differentiation Cell Differentiation Development Of Primary Sexual Characteristics
Pathways			Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases			46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS			Brain morphology (MOSTest) ( 32665545)
Interacting Genes		28 interacting genes: APOBEC3C CBX2 CNNM3 EPM2AIP1 HHEX HNRNPK LNX1 NPDC1 PCDHB14 PPP1R37 PRPF31 PRR3 RASD1 RBM3 RBMX RBMY1A1 RBMY1E RBMY1F RNPS1 SNRPA SPATC1L TRA2B U2AF2 YTHDC1 ZNF317 ZNF408 ZNF792 ZNF837	25 interacting genes: BOLL CYSRT1 DHX57 H3-3A H3-4 H3C1 H3C14 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-4 KRTAP4-12 KRTAP4-4 MDFI MEOX2 RBMY1A1 RBMY1F RBMY1J RBPMS2 RYBP TRIM55 TRIM63
Entrez ID		378951	84733
HPRD ID		15233	14397
Ensembl ID		ENSG00000226941	ENSG00000173894
Uniprot IDs		Q15415	Q14781
PDB IDs			2D9U 3H91 5EPK
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Spliceosomal Complex Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing MRNA Processing Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nucleic Acid Binding RNA Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleus Regulation Of Gene Expression MRNA Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Ribonucleoprotein Complex Localization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cytoplasmic Translational Initiation Ribonucleoprotein Complex Poly-pyrimidine Tract Binding U4atac SnRNP	Keratin Filament Intermediate Filament Structural Constituent Of Chromatin Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding Nucleosome Assembly Regulation Of MRNA Splicing, Via Spliceosome Nucleosome Positive Regulation Of RNA Splicing Nucleosome Organization Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Protein-DNA Complex Assembly Hair Cycle Identical Protein Binding Positive Regulation Of MRNA Metabolic Process Protein Heterodimerization Activity Chromatin Remodeling Spliceosomal Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?