BACH2 and NFE2L1

Number of citations of the paper that reports this interaction (PMID 23661758)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		BACH2	NFE2L1
Gene Name		BTB and CNC homology 1, basic leucine zipper transcription factor 2	nuclear factor, erythroid 2-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Transcription From RNA Polymerase II Promoter Heme Biosynthetic Process Inflammatory Response Anatomical Structure Morphogenesis Erythrocyte Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Cognitive performance ( 20125193) Crohn's disease ( 21102463) Graves' disease ( 21841780) IgG glycosylation ( 23382691) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 23273568) Type 1 diabetes ( 19430480 18840781 18978792) Type 1 diabetes autoantibodies ( 21829393) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22561518)	Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		8 interactors: BATF3 DDIT3 MAFF MAFG MAFK NFE2L1 NFE2L3 PATZ1	14 interactors: ATF4 BACH2 CAPN1 CD6 CREBZF GSK3B HCFC1 JUN JUNB JUND MAFF MAFG MAFK NFE2L3
Entrez ID		60468	4779
HPRD ID		12012	01223
Ensembl ID		ENSG00000112182	ENSG00000082641
Uniprot IDs		Q9BYV9	B4DYE1 F5H1B7 J3QKY3 J9JIE5 Q14494 Q8NF22
PDB IDs		3OHU 3OHV
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Regulation Of Epidermal Cell Differentiation Regulation Of Metabolic Process Anatomical Structure Development Regulation Of Epidermis Development Developmental Process Negative Regulation Of Transcription, DNA-templated Blood Coagulation Negative Regulation Of Nucleic Acid-templated Transcription Hemostasis Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Gene Expression System Development Negative Regulation Of Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Body Fluid Levels Wound Healing Hemopoiesis Regulation Of Epithelial Cell Differentiation Cellular Metabolic Process Response To Wounding Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Transcription From RNA Polymerase II Promoter Response To Stress Myeloid Cell Differentiation ER Overload Response Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process MRNA Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Cellular Response To Calcium Ion Negative Regulation Of Biosynthetic Process Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Rhythmic Process Negative Regulation Of RNA Biosynthetic Process Response To Metal Ion Response To Calcium Ion Regulation Of Metabolic Process Cellular Response To Metal Ion Positive Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Differentiation Cellular Response To Inorganic Substance Negative Regulation Of Cellular Metabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Macromolecule Biosynthetic Process Response To Inorganic Substance Positive Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Epidermal Cell Differentiation Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Wounding Positive Regulation Of Neuron Apoptotic Process
Tagcloud ?		architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper	11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine p45 seen sequence shows similar similarity subunit zipper
Tagcloud (Difference) ?		architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly	11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine p45 seen sequence shows similar similarity subunit
Tagcloud (Intersection) ?		zipper