BACH2

Gene Name		BTB and CNC homology 1, basic leucine zipper transcription factor 2
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Cognitive performance ( 20125193) Crohn's disease ( 21102463) Graves' disease ( 21841780) IgG glycosylation ( 23382691) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 23273568) Type 1 diabetes ( 19430480 18840781 18978792) Type 1 diabetes autoantibodies ( 21829393) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22561518)
Protein-protein Interactions		8 interactors: BATF3 DDIT3 MAFF MAFG MAFK NFE2L1 NFE2L3 PATZ1
Entrez ID		60468
HPRD ID		12012
Ensembl ID		ENSG00000112182
Uniprot IDs		Q9BYV9
PDB IDs		3OHU 3OHV
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Regulation Of Epidermal Cell Differentiation Regulation Of Metabolic Process Anatomical Structure Development Regulation Of Epidermis Development Developmental Process Negative Regulation Of Transcription, DNA-templated Blood Coagulation Negative Regulation Of Nucleic Acid-templated Transcription Hemostasis Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Gene Expression System Development Negative Regulation Of Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Body Fluid Levels Wound Healing Hemopoiesis Regulation Of Epithelial Cell Differentiation Cellular Metabolic Process Response To Wounding Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Transcription From RNA Polymerase II Promoter Response To Stress Myeloid Cell Differentiation ER Overload Response Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process MRNA Transcription From RNA Polymerase II Promoter
Tagcloud ?		architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper