BACH2 and PATZ1

Number of citations of the paper that reports this interaction (PMID 10669750)
27

Data Source:
HPRD (in vivo, two hybrid)

		BACH2	PATZ1
Gene Name		BTB and CNC homology 1, basic leucine zipper transcription factor 2	POZ (BTB) and AT hook containing zinc finger 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription	DNA Binding Chromatin Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Male Gonad Development T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Cognitive performance ( 20125193) Crohn's disease ( 21102463) Graves' disease ( 21841780) IgG glycosylation ( 23382691) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 23273568) Type 1 diabetes ( 19430480 18840781 18978792) Type 1 diabetes autoantibodies ( 21829393) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22561518)
Protein-Protein Interactions		8 interactors: BATF3 DDIT3 MAFF MAFG MAFK NFE2L1 NFE2L3 PATZ1	6 interactors: BACH1 BACH2 MITF PRKAR1A RNF4 TP53
Entrez ID		60468	23598
HPRD ID		12012	05522
Ensembl ID		ENSG00000112182	ENSG00000100105
Uniprot IDs		Q9BYV9	Q9HBE1
PDB IDs		3OHU 3OHV	2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Regulation Of Epidermal Cell Differentiation Regulation Of Metabolic Process Anatomical Structure Development Regulation Of Epidermis Development Developmental Process Negative Regulation Of Transcription, DNA-templated Blood Coagulation Negative Regulation Of Nucleic Acid-templated Transcription Hemostasis Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Gene Expression System Development Negative Regulation Of Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Body Fluid Levels Wound Healing Hemopoiesis Regulation Of Epithelial Cell Differentiation Cellular Metabolic Process Response To Wounding Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Transcription From RNA Polymerase II Promoter Response To Stress Myeloid Cell Differentiation ER Overload Response Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process MRNA Transcription From RNA Polymerase II Promoter	Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Macromitophagy Regulation Of Kinetochore Assembly Oligodendrocyte Apoptotic Process Double-strand Break Repair DNA Damage Checkpoint Negative Regulation Of Helicase Activity Regulation Of Centromere Complex Assembly Gastrulation Regulation Of Metabolic Process Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Chromosome Organization Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Mitochondrial DNA Repair
Tagcloud ?		architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary poz proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Difference) ?		architectural architecture bach1 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening properly zipper	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Intersection) ?		poz