NFE2L1 and MAFG

Number of citations of the paper that reports this interaction (PMID 9421508)
32

Data Source:
BioGRID (fluorescent resonance energy transfer)
HPRD (in vitro)

		NFE2L1	MAFG
Gene Name		nuclear factor, erythroid 2-like 1	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleoplasm
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Heme Biosynthetic Process Inflammatory Response Anatomical Structure Morphogenesis Erythrocyte Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter	In Utero Embryonic Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Blood Coagulation Adult Behavior Regulation Of Cellular PH Regulation Of Cell Proliferation Regulation Of Epidermal Cell Differentiation
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		14 interactors: ATF4 BACH2 CAPN1 CD6 CREBZF GSK3B HCFC1 JUN JUNB JUND MAFF MAFG MAFK NFE2L3	26 interactors: ATF3 BACH1 BACH2 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOXD12 MAF MAFF MED31 NFE2 NFE2L1 NFE2L2 NFE2L3 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM
Entrez ID		4779	4097
HPRD ID		01223	03605
Ensembl ID		ENSG00000082641	ENSG00000197063
Uniprot IDs		B4DYE1 F5H1B7 J3QKY3 J9JIE5 Q14494 Q8NF22	O15525
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Cellular Response To Calcium Ion Negative Regulation Of Biosynthetic Process Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Rhythmic Process Negative Regulation Of RNA Biosynthetic Process Response To Metal Ion Response To Calcium Ion Regulation Of Metabolic Process Cellular Response To Metal Ion Positive Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Differentiation Cellular Response To Inorganic Substance Negative Regulation Of Cellular Metabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Macromolecule Biosynthetic Process Response To Inorganic Substance Positive Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Epidermal Cell Differentiation Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Wounding Positive Regulation Of Neuron Apoptotic Process	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Process Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Cellular Metabolic Process Limb Development Positive Regulation Of Stem Cell Proliferation Response To Stress Developmental Process MRNA Transcription From RNA Polymerase II Promoter System Development Organ Development
Tagcloud ?		11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine p45 seen sequence shows similar similarity subunit zipper	albeit arrested asymmetric constitute dimerizes dissect e2 erythroid heterodimeric lineages livers maff mafk megakaryocyte megakaryocytes megakaryocytic mpl nucleotides outside p18 p45 polypeptides predominate profound rarity readily recognizes thrombocytopenia
Tagcloud (Difference) ?		11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine seen sequence shows similar similarity subunit zipper	albeit arrested asymmetric constitute dimerizes dissect erythroid heterodimeric lineages livers maff mafk megakaryocyte megakaryocytes megakaryocytic mpl nucleotides outside p18 polypeptides predominate profound rarity readily recognizes thrombocytopenia
Tagcloud (Intersection) ?		e2 p45