DEAF1 and RAD23B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DEAF1	RAD23B
Gene Name		DEAF1 transcription factor	RAD23 homolog B (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm	Proteasome Complex Nucleus Nucleoplasm Cytoplasm XPC Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Binding
	Biological Process	Behavioral Fear Response Neural Tube Closure Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Germ Cell Development Visual Learning Anatomical Structure Morphogenesis Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER DNA Damage Recognition in GG-NER Dual incision reaction in GG-NER
Drugs
Diseases
GWAS			Body mass index ( 20966902) Breast cancer ( 21263130) Prostate cancer ( 23023329)
Protein-Protein Interactions		18 interactors: AIMP2 ASCC2 CDC37 CDKN1A CDKN2A FHL1 GSK3A GSK3B HRAS HRSP12 INTS1 LMO4 PELI2 PIN1 PPP1CA PPP1CC RAD23B TK1	20 interactors: ADRM1 ATXN3 CALM1 DBI DEAF1 HMGB1 MLH1 MPG NGLY1 PAX3 PNMA5 PSMD4 PUF60 RPA1 TDG UBA2 UBB UBE3A XPC ZFAND5
Entrez ID		10522	5887
HPRD ID		04027	06772
Ensembl ID		ENSG00000177030	ENSG00000119318
Uniprot IDs		O75398	B7Z4W4 P54727
PDB IDs		2JW6 4A24	1P1A 1PVE 1UEL
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Glycogen Metabolic Process Positive Regulation Of Protein Modification Process Polysaccharide Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Senescence Regulation Of Glycogen Biosynthetic Process Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Hypermethylation Of CpG Island Energy Reserve Metabolic Process Regulation Of Glycogen Metabolic Process Response To Growth Factor Regulation Of Cellular Component Organization Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Cell Growth Cellular Response To Interleukin-3 Programmed Cell Death Regulation Of Phosphorus Metabolic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Death Death Tube Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Mitotic Cell Cycle Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Protein Kinase Activity Response To Fibroblast Growth Factor Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Innate Immune Response Immune Response-regulating Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Aging Fc-epsilon Receptor Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Cellular Carbohydrate Metabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy	Cellular Macromolecule Catabolic Process Catabolic Process Cellular Response To DNA Damage Stimulus DNA Repair DNA Catabolic Process Base-excision Repair DNA Metabolic Process Nitrogen Compound Metabolic Process Aromatic Compound Catabolic Process Cellular Response To Stress Response To Stress Cellular Nitrogen Compound Metabolic Process Protein Catabolic Process Mismatch Repair Cellular Metabolic Process Base-excision Repair, AP Site Formation Modification-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair Mitotic DNA Damage Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Mitotic DNA Integrity Checkpoint Multicellular Organismal Development Positive Regulation Of Proteolysis Heterocycle Metabolic Process Deoxyribose Phosphate Catabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Process Nucleotide-excision Repair, DNA Damage Removal Anatomical Structure Development Programmed Cell Death System Development Cell Death Death Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Response To Abiotic Stimulus Deoxyribonucleotide Catabolic Process DNA Damage Checkpoint Nervous System Development G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Protein Polyubiquitination Developmental Process Behavioral Fear Response Fear Response Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process
Tagcloud ?		abundantly believed carcinomas cardiomyocyte dysfunction enhancer epigenetic gather growing interest list making methylate myeloid mynd myogenesis nervy putative regulator relevance remodeling skeletal smyd suppressor transduction trithorax variegation variety zeste	a3 adoptive bioinformatic blunting dige diploid disulfide excision galactosidase hnrnpa3 hnrnpq imr90 isomerase lesser mir mirrored pdia3 permanent perturbation proteome ribonucleoprotein senescence senescent slowed synaptotagmin syncrip untranslated utrs
Tagcloud (Difference) ?		abundantly believed carcinomas cardiomyocyte dysfunction enhancer epigenetic gather growing interest list making methylate myeloid mynd myogenesis nervy putative regulator relevance remodeling skeletal smyd suppressor transduction trithorax variegation variety zeste	a3 adoptive bioinformatic blunting dige diploid disulfide excision galactosidase hnrnpa3 hnrnpq imr90 isomerase lesser mir mirrored pdia3 permanent perturbation proteome ribonucleoprotein senescence senescent slowed synaptotagmin syncrip untranslated utrs
Tagcloud (Intersection) ?