ZNF557 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		ZNF557	SUV39H2
Description		zinc finger protein 557	SUV39H2 histone lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia
Pathways		Generic Transcription Pathway	PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		14 interacting genes: CCDC125 CCNDBP1 CEP70 CRK GOLGA6L9 MTUS2 NSD3 PRMT6 SMAD9 SMYD3 STAT3 STX1A SUV39H1 SUV39H2	43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57
Entrez ID		79230	79723
HPRD ID		15840	07580
Ensembl ID		ENSG00000130544	ENSG00000152455
Uniprot IDs		Q8N988	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?		Histone Methyltransferase Activity Histone H3 Methyltransferase Activity Methyltransferase Activity Methylation Histone H3K9 Trimethyltransferase Activity Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Chromatin Remodeling Epigenetic Programming Of Gene Expression Chromatin Organization	Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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