ZNF557 and SMYD3

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		ZNF557	SMYD3
Gene Name		zinc finger protein 557	SET and MYND domain containing 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Metal Ion Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Chromatin Organization Nucleosome Assembly Negative Regulation Of Protein Kinase Activity Myotube Cell Development Positive Regulation Of Peptidyl-serine Phosphorylation Histone Lysine Methylation Establishment Of Protein Localization Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Dexamethasone Stimulus
Pathways		Generic Transcription Pathway	Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: PRMT6 SMAD9 SMYD3 SUV39H1 SUV39H2 WHSC1L1	16 interactors: APP CAMK2B CYP39A1 EED EZH2 H3F3C HELZ HIST3H3 HSP90AA1 NDUFAB1 NFYB PBX2 POLR2K TRIT1 VANGL1 ZNF557
Entrez ID		79230	64754
HPRD ID		15840	12297
Ensembl ID		ENSG00000130544	ENSG00000185420
Uniprot IDs		Q8N988	B3KN46 Q9H7B4
PDB IDs			3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0
Enriched GO Terms of Interacting Partners?		Histone Methylation Protein Methylation Histone Lysine Methylation Peptidyl-lysine Methylation Histone Modification Methylation Chromatin Modification Chromatin Organization Peptidyl-lysine Modification Histone H3-K9 Dimethylation Peptidyl-amino Acid Modification Chromosome Organization Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Cellular Protein Modification Process Negative Regulation Of Circadian Rhythm Histone H3-K9 Methylation Peptidyl-lysine Trimethylation Histone H3-K9 Modification Negative Regulation Of Cellular Metabolic Process Response To Hypoxia Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Metabolic Process Organelle Organization Regulation Of Circadian Rhythm RNA Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Histone H3-R2 Methylation Chromatin Assembly Or Disassembly Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process	Negative Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Heat Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Inhibitory G-protein Coupled Receptor Phosphorylation Positive Regulation Of Cellular Metabolic Process Cellular Response To Heat Neuromuscular Process Controlling Balance Synaptic Growth At Neuromuscular Junction Activation Of Meiosis Involved In Egg Activation Innate Immune Response Regulation Of Synapse Structure Or Activity Cellular Metabolic Process Bile Acid Catabolic Process Collateral Sprouting In Absence Of Injury Response To Heat Transcription, DNA-templated Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Protein Import Into Mitochondrial Outer Membrane Activation Of Meiosis Cholesterol Metabolic Process Histone Methylation Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Protein Lipoylation Sterol Metabolic Process Neuromuscular Process Regulation Of Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Metabolic Process Gene Expression Regulation Of Synaptic Transmission, Cholinergic Axon Choice Point Recognition
Tagcloud ?			blocked bovine conversely early embryonic embryos epigenetic fertilization germinal involves lysine mammalian maturation methyltransferase microinjection modifications mynd nanog oocyte oocytes plays program pronuclear regulates reprogramming sirna stage throughout vesicle
Tagcloud (Difference) ?			blocked bovine conversely early embryonic embryos epigenetic fertilization germinal involves lysine mammalian maturation methyltransferase microinjection modifications mynd nanog oocyte oocytes plays program pronuclear regulates reprogramming sirna stage throughout vesicle
Tagcloud (Intersection) ?