C19orf57 and VCL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		C19orf57	VCL
Gene Name		chromosome 19 open reading frame 57	vinculin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Extracellular Region Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Actin Cytoskeleton Cell-substrate Junction Vesicle Costamere Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Protein Binding	Dystroglycan Binding Actin Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Alpha-catenin Binding Cadherin Binding
	Biological Process	Multicellular Organismal Development	Morphogenesis Of An Epithelium Platelet Degranulation Movement Of Cell Or Subcellular Component Muscle Contraction Cell Adhesion Cell-matrix Adhesion Blood Coagulation Lamellipodium Assembly Platelet Activation Negative Regulation Of Cell Migration Adherens Junction Assembly Protein Localization To Cell Surface Apical Junction Assembly Axon Extension Platelet Aggregation Epithelial Cell-cell Adhesion
Pathways			Response to elevated platelet cytosolic Ca2+ Smooth Muscle Contraction Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS			Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		24 interactors: AIMP2 APP C19orf25 CENPQ COPS4 CTNNAL1 EWSR1 FAM9B FBXO25 GPS2 HAUS3 HOMER1 IKBKG KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 PSMA6 RABL6 RUNX1T1 TRIM23 TSC22D3 VCL	27 interactors: ABI2 ACTA1 ACTN1 C19orf57 CDH1 CLTC CORO2B CTNNA1 GSN NRAP PKD1 PRKCA PRPF40A PSME1 PTK2 PXN RAVER1 SELE SORBS1 SORBS2 SRC TEKT1 TGFB1I1 TLN1 TRIP6 TUBA1A VASP
Entrez ID		79173	7414
HPRD ID		14415	01900
Ensembl ID		ENSG00000132016	ENSG00000035403
Uniprot IDs		Q0VDD7	B3KXA2 P18206
PDB IDs			1RKC 1RKE 1SYQ 1TR2 1YDI 2GWW 2HSQ 2IBF 3H2U 3H2V 3MYI 3RF3 3S90 3TJ5 3TJ6 3VF0 4DJ9 4EHP
Enriched GO Terms of Interacting Partners?			Cytoskeleton Organization Cell Junction Assembly Cell-cell Junction Organization Actin Filament-based Process Organelle Organization Adherens Junction Organization Actin Filament Organization Actin Cytoskeleton Organization Cell Adhesion Cellular Component Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-substrate Junction Assembly Regulation Of Cellular Component Organization Regulation Of Cellular Component Movement Focal Adhesion Assembly Signal Complex Assembly Cell-cell Junction Assembly Cell-substrate Adhesion Movement Of Cell Or Subcellular Component Adherens Junction Assembly Regulation Of Cell Motility Positive Regulation Of Signal Transduction Regulation Of Locomotion Response To Organic Substance Response To Wounding Cell-matrix Adhesion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cell Projection Organization Cell Differentiation Positive Regulation Of Transferase Activity Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Anatomical Structure Morphogenesis Regulation Of Body Fluid Levels Platelet Activation Regulation Of Cell Migration Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Locomotion Blood Coagulation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Hemostasis Cellular Response To Stimulus Protein Complex Assembly Cell Development Cellular Response To Organonitrogen Compound Integrin-mediated Signaling Pathway Cellular Response To Organic Substance
Tagcloud ?			34a 34c analyse chimeras crick destabilizing differs fkbp8 implement micrornas mir mirna nucleotides observe overlap overlapping pairing perfect preferential psilac raising repress repressed resource seed subsets untranslated want watson
Tagcloud (Difference) ?			34a 34c analyse chimeras crick destabilizing differs fkbp8 implement micrornas mir mirna nucleotides observe overlap overlapping pairing perfect preferential psilac raising repress repressed resource seed subsets untranslated want watson
Tagcloud (Intersection) ?