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VCL and BRME1
Number of citations of the paper that reports this interaction (PubMedID
16189514
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
VCL
BRME1
Description
vinculin
break repair meiotic recombinase recruitment factor 1
Image
GO Annotations
Cellular Component
Podosome
Extracellular Region
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Brush Border
Cell-cell Junction
Adherens Junction
Zonula Adherens
Fascia Adherens
Focal Adhesion
Actin Cytoskeleton
Membrane
Myofibril
Cell-substrate Junction
Protein-containing Complex
Secretory Granule Lumen
Specific Granule Lumen
Sarcolemma
Cell Projection
Costamere
Cell-cell Contact Zone
Membrane Raft
Perinuclear Region Of Cytoplasm
Podosome Ring
Extracellular Exosome
Anchoring Junction
Outer Dense Plaque Of Desmosome
Inner Dense Plaque Of Desmosome
Extracellular Vesicle
Ficolin-1-rich Granule Lumen
Terminal Web
Chromosome
Molecular Function
Dystroglycan Binding
Actin Binding
Structural Molecule Activity
Protein Binding
Beta-catenin Binding
Ubiquitin Protein Ligase Binding
Alpha-catenin Binding
Cadherin Binding
Molecular Adaptor Activity
Protein Binding
Biological Process
Morphogenesis Of An Epithelium
Cell Adhesion
Cell-matrix Adhesion
Lamellipodium Assembly
Regulation Of Cell Migration
Negative Regulation Of Cell Migration
Adherens Junction Assembly
Protein Localization To Cell Surface
Maintenance Of Blood-brain Barrier
Apical Junction Assembly
Axon Extension
Regulation Of Focal Adhesion Assembly
Platelet Aggregation
Epithelial Cell-cell Adhesion
Regulation Of Establishment Of Endothelial Barrier
Regulation Of Protein Localization To Adherens Junction
Female Meiosis I
Spermatogenesis
Meiotic Cell Cycle
Double-strand Break Repair Involved In Meiotic Recombination
Pathways
Platelet degranulation
Smooth Muscle Contraction
MAP2K and MAPK activation
Neutrophil degranulation
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
Signaling by ALK fusions and activated point mutants
Regulation of CDH1 Function
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Drugs
Diseases
GWAS
Cardiac troponin-I levels (
31014085
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Left ventricular internal dimension in diastole (
29403010
)
Primary tooth development (number of teeth) (
23704328
)
Primary tooth development (time to first tooth eruption) (
23704328
)
Refractive error (
32231278
)
Interacting Genes
38 interacting genes:
ABI2
ACTA1
ACTN1
BCAR1
BIRC6
BRME1
CDH1
CLTC
CORO2B
CTNNA1
ENOX2
GSN
ITGA5
LINC01554
LPXN
NEBL
NRAP
PKD1
POMP
PRKCA
PRPF40A
PSME1
PTK2
PXN
RAVER1
SAPCD2
SELE
SORBS1
SORBS2
SORBS3
SRC
TEKT1
TGFB1I1
TLN1
TRIM15
TRIP6
TUBA1A
VASP
33 interacting genes:
ADAMTSL4
AIMP2
APP
C19orf25
CENPQ
COPS4
CTNNAL1
CYSRT1
EWSR1
FAM9B
FBXO25
GPS2
HAUS3
HOMER1
IKBKG
KRT31
KRT34
KRT38
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP5-9
NBPF19
NOTCH2NLA
PSMA6
RABL6
RUNX1T1
STXBP1
TRIM23
TSC22D3
VCL
Entrez ID
7414
79173
HPRD ID
01900
14415
Ensembl ID
ENSG00000035403
ENSG00000132016
Uniprot IDs
B3KXA2
P18206
V9HWK2
K7EMZ7
Q0VDD7
PDB IDs
1RKC
1RKE
1SYQ
1TR2
1YDI
2GWW
2HSQ
2IBF
3H2U
3H2V
3JBK
3MYI
3RF3
3S90
3TJ5
3TJ6
3VF0
4DJ9
4EHP
4LN2
4LNP
4PR9
5L0C
5L0D
5L0F
5L0G
5L0H
5L0I
5L0J
5O2Q
6FUY
6UPW
7KTT
7KTU
7KTV
7KTW
8A51
Enriched GO Terms of Interacting Partners
?
Anchoring Junction
Focal Adhesion
Vinculin Binding
Cell-substrate Junction Assembly
Cell-substrate Junction Organization
Cell Junction Assembly
Cell Adhesion
Cytoskeleton
Actin Filament Organization
Cell Junction Organization
Lamellipodium
Supramolecular Fiber Organization
Stress Fiber
Cellular Component Assembly
Focal Adhesion Assembly
Actin Cytoskeleton
Cytoplasm
Cell-substrate Adhesion
Integrin-mediated Signaling Pathway
Cytoskeleton Organization
Actin Binding
Cell Motility
Actin Filament Binding
Cell Migration
Signal Complex Assembly
Integrin Binding
Flotillin Complex
Regulation Of Cytoskeleton Organization
Actin Filament-based Process
Structural Constituent Of Cytoskeleton
Regulation Of Cell Adhesion
Cell-cell Junction Assembly
Negative Regulation Of Anoikis
Actin Cytoskeleton Organization
Cardiac Muscle Thin Filament Assembly
Cytoskeletal Protein Binding
Regulation Of Actin Filament Organization
Regulation Of Anoikis
Regulation Of Cellular Component Organization
Positive Regulation Of Supramolecular Fiber Organization
Actin Filament
Plasma Membrane
Cell-cell Junction Organization
Cellular Response To Indole-3-methanol
Cytosol
Positive Regulation Of Cytoskeleton Organization
Cell Projection
Adherens Junction
Protein-containing Complex Assembly
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Intermediate Filament
Keratin Filament
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Cytosol
Intermediate Filament Cytoskeleton Organization
Structural Molecule Activity
Intermediate Filament-based Process
Epidermis Development
Regulation Of Dendritic Spine Maintenance
Costamere
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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