PLEKHF1 and L3MBTL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PLEKHF1	L3MBTL3
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 1	l(3)mbt-like 3 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Lysosome Lysosomal Membrane Endosome Endosome Membrane Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Molecular_function
	Biological Process	Apoptotic Process Endosome Organization Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation
Pathways
Drugs
Diseases
GWAS			Height ( 20881960 23563607 18391951)
Protein-Protein Interactions		3 interactors: KIAA1279 L3MBTL3 TNNT1	26 interactors: ASB6 BANP BYSL KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SP100 SUMO1P1 THRA TTC19
Entrez ID		79156	84456
HPRD ID		15146	11222
Ensembl ID		ENSG00000166289	ENSG00000198945
Uniprot IDs		B4DWN9 Q96S99	Q96JM7
PDB IDs			1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?		Slow-twitch Skeletal Muscle Fiber Contraction Erythrocyte Maturation Granulocyte Differentiation Macrophage Differentiation Negative Regulation Of Muscle Contraction Skeletal Muscle Contraction Muscle Filament Sliding Actin-myosin Filament Sliding Erythrocyte Development Musculoskeletal Movement Actin-mediated Cell Contraction Actin Filament-based Movement	Positive Regulation Of Autophagy Chromatin Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Binding RNA Metabolic Process Regulation Of Autophagy Chromatin Organization Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Biosynthetic Process Regulation Of Lipid Metabolic Process Cellular Response To Stress Activation Of MAPK Activity Insulin Receptor Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Transport Chromosome Organization Gene Expression Positive Regulation Of MAP Kinase Activity Cellular Response To Insulin Stimulus Regulation Of Energy Homeostasis Regulation Of Apoptotic Process Positive Regulation Of Glycolytic Process Negative Regulation Of Intracellular Protein Transport Fatty Acid Homeostasis Positive Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Regulation Of Cell Death Cellular Nitrogen Compound Metabolic Process Regulation Of Binding Regulation Of Circadian Rhythm Organelle Organization Response To Organonitrogen Compound Regulation Of Metabolic Process Activation Of Protein Kinase Activity Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Nucleobase-containing Compound Metabolic Process Regulation Of MAP Kinase Activity Response To Insulin Negative Regulation Of Intracellular Transport Histone-serine Phosphorylation Regulation Of Signal Transduction Peptidyl-serine Phosphorylation Regulation Of Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Hormone Stimulus Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Glucose Starvation
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