PLEKHF1 and KIFBP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHF1	KIFBP
Description		pleckstrin homology and FYVE domain containing 1	kinesin family binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Endosome Early Endosome Endosome Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Cytoskeleton
	Molecular Function	Protein Binding Zinc Ion Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Protein Binding Kinesin Binding Protein Sequestering Activity
	Biological Process	Apoptotic Process Endosome Organization Endosome To Lysosome Transport Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane	Microtubule Cytoskeleton Organization In Utero Embryonic Development Nervous System Development Transport Along Microtubule Central Nervous System Projection Neuron Axonogenesis Cell Differentiation Mitochondrion Transport Along Microtubule Neuron Projection Maintenance
Pathways
Drugs
Diseases			Goldberg-Shprintzen megacolon syndrome; Goldberg-Shprintzen syndrome (GOSHS) Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS		Body mass index ( 26426971)
Interacting Genes		7 interacting genes: CAVIN2 CHIC2 KIFBP L3MBTL3 NPM2 TNFAIP8 TNNT1	10 interacting genes: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670
Entrez ID		79156	26128
HPRD ID		15146	13848
Ensembl ID		ENSG00000166289	ENSG00000198954
Uniprot IDs		B4DWN9 Q96S99	Q96EK5
PDB IDs			6ZPG 6ZPH 7RSI 7RSQ 7RYP 7RYQ
Enriched GO Terms of Interacting Partners?		Slow-twitch Skeletal Muscle Fiber Contraction Troponin T Binding Oocyte Differentiation Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Methylation-dependent Protein Binding	Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Leukotriene D4 Catabolic Process GPI Anchor Binding Beta-lactamase Activity Glutathione Catabolic Process Modified Amino Acid Binding Metallodipeptidase Activity Photoreceptor Activity Regulation Of Establishment Of Protein Localization To Chromosome Nuclear Telomere Cap Complex Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Telomere Localization Shelterin Complex Meiotic Telomere Clustering Telomeric D-loop Disassembly Ankyrin Repeat Binding Double-stranded Telomeric DNA Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) 7S RNA Binding TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process U4 SnRNA 3'-end Processing CUT Catabolic Process Poly(A)-dependent SnoRNA 3'-end Processing
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