PLEKHF1 and KIAA1279

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHF1	KIAA1279
Gene Name		pleckstrin homology domain containing, family F (with FYVE domain) member 1	KIAA1279
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Lysosome Lysosomal Membrane Endosome Endosome Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Cytoskeleton
	Molecular Function	Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Protein Binding Kinesin Binding
	Biological Process	Apoptotic Process Endosome Organization Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrial Transport Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: KIAA1279 L3MBTL3 TNNT1	10 interactors: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670
Entrez ID		79156	26128
HPRD ID		15146	13848
Ensembl ID		ENSG00000166289	ENSG00000198954
Uniprot IDs		B4DWN9 Q96S99	Q96EK5
PDB IDs
Enriched GO Terms of Interacting Partners?		Slow-twitch Skeletal Muscle Fiber Contraction Erythrocyte Maturation Granulocyte Differentiation Macrophage Differentiation Negative Regulation Of Muscle Contraction Skeletal Muscle Contraction Muscle Filament Sliding Actin-myosin Filament Sliding Erythrocyte Development Musculoskeletal Movement Actin-mediated Cell Contraction Actin Filament-based Movement	Positive Regulation Of Chylomicron Remnant Clearance Cellular Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Cellular Process G2/M Transition Of Mitotic Cell Cycle Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Microtubule Cytoskeleton Organization Telomere Maintenance Via Telomere Shortening Regulation Of Microtubule-based Process Regulation Of Metabolic Process Response To Heparin Negative Regulation Of Telomere Maintenance Via Telomerase Homocysteine Metabolic Process Replicative Cell Aging Negative Regulation Of Receptor Internalization Regulation Of Nuclear Cell Cycle DNA Replication Cytoplasmic MRNA Processing Body Assembly Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Centriole Replication Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Transcytosis Positive Regulation Of Microtubule Polymerization Cellular Response To Nitric Oxide Regulation Of Cell Cycle Cerebellar Purkinje Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Protein-chromophore Linkage Heterocycle Metabolic Process Regulation Of Telomerase Activity Stress Granule Assembly Response To Nitric Oxide
Tagcloud ?			arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr
Tagcloud (Difference) ?			arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr
Tagcloud (Intersection) ?