PLEKHF1 and CAVIN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLEKHF1	CAVIN2
Description		pleckstrin homology and FYVE domain containing 1	caveolae associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Endosome Early Endosome Endosome Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Caveola Membrane Membrane Raft
	Molecular Function	Protein Binding Zinc Ion Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Phosphatidylserine Binding Protein Kinase C Binding Protein Binding Phospholipid Binding Lipid Binding
	Biological Process	Apoptotic Process Endosome Organization Endosome To Lysosome Transport Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane	Plasma Membrane Tubulation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Diffusing capacity of carbon monoxide ( 30694715)
Interacting Genes		7 interacting genes: CAVIN2 CHIC2 KIFBP L3MBTL3 NPM2 TNFAIP8 TNNT1	8 interacting genes: A1CF MCRS1 NUDT18 PLEKHF1 PLEKHF2 PRKCA TRAPPC6A TRIM54
Entrez ID		79156	8436
HPRD ID		15146	09470
Ensembl ID		ENSG00000166289	ENSG00000168497
Uniprot IDs		B4DWN9 Q96S99	O95810
PDB IDs
Enriched GO Terms of Interacting Partners?		Slow-twitch Skeletal Muscle Fiber Contraction Troponin T Binding Oocyte Differentiation Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Methylation-dependent Protein Binding	Vesicle Organization Endosome To Lysosome Transport 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity MRNA Localization Resulting In Post-transcriptional Regulation Of Gene Expression Endosome Organization Phosphatidylinositol Binding 8-oxo-dGDP Phosphatase Activity GDP Catabolic Process Lysosomal Transport Protein Kinase C Signaling MRNA Editing Complex
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