TAF1D and FAF1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TAF1D	FAF1
Description		TATA-box binding protein associated factor, RNA polymerase I subunit D	Fas associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Endomembrane System CD95 Death-inducing Signaling Complex VCP-NPL4-UFD1 AAA ATPase Complex Perinuclear Region Of Cytoplasm Ooplasm
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding Protein Kinase Regulator Activity Protein Kinase Binding Protein Domain Specific Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding NF-kappaB Binding
	Biological Process	Regulation Of DNA-templated Transcription	Apoptotic Process Regulation Of Cell Adhesion Fas Signaling Pathway ERAD Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Atrial fibrillation ( 29290336) Blood urea nitrogen levels ( 31152163) Body mass index and type 2 diabetes (pairwise) ( 33619380) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Depression and alcohol dependence ( 22064162) FEV1 ( 30804560) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412 34021172) Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459) Ischemic stroke (large artery atherosclerosis) ( 26732560) Left ventricle wall thickness ( 33495596) Left ventricular mass to end-diastolic volume ratio ( 33495596) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung function (FEV1/FVC) ( 30804560) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Mean reticulocyte volume ( 32888494) Multisite chronic pain ( 33830993 31194737) Neutrophil percentage of white cells ( 32888494) Pancreas fat ( 34128465) Peak expiratory flow ( 30804560) Postprandial triglyceride response ( 32603185) Pulse pressure ( 30578418 27841878) QRS duration ( 21076409 30679814) Renal cell carcinoma ( 28598434) Reticulocyte fraction of red cells ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 24509480 26818947 28869590 30718926 32499647) Ventricular ectopy ( 29618737) Ventricular ectopy or supraventricular ectopy (pleiotropy) ( 29618737)
Interacting Genes		23 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TMSB4X UBE2D1 UBTF	49 interacting genes: AKT1 ANXA1 ANXA7 ASCC2 CASP8 CBS CD40 CDC73 CDKN1A CREBBP CSNK2A1 CSNK2B DNAJB11 FADD FAF2 FAS HSD17B10 HSPA1B IGF2 IKBKB ITGB1BP1 NEDD8 NGLY1 NLRP12 NLRP2 NLRP3 NLRP7 NR1H2 NR4A1 PRKN RAP1A RAP1B RCC1 RELA SIRT6 SKIL SNIP1 SPOP SUMO1 TAF1D TK1 TNNT1 TSC22D1 UBC UBE2I UROD WWP2 XIAP YTHDF3
Entrez ID		79101	11124
HPRD ID		14679	05124
Ensembl ID		ENSG00000166012	ENSG00000185104
Uniprot IDs		Q9H5J8	Q9UNN5
PDB IDs			1H8C 2DZM 2EC4 3E21 3QC8 3QCA 3QQ8 3QWZ 3QX1 3R3M 7FGM 7FGN 8KG2
Enriched GO Terms of Interacting Partners?		Regulation Of Glucose Mediated Signaling Pathway RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Regulation Of Organelle Transport Along Microtubule Regulation Of Stem Cell Differentiation Positive Regulation Of Dendrite Development Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Protein Kinase Regulator Activity Ovulation Cycle Protein-containing Complex Regulation Of Microtubule-based Process Regulation Of Cell Communication Negative Regulation Of Stem Cell Differentiation Regulation Of Signaling Regulation Of Cell Differentiation Positive Regulation Of Cation Channel Activity Regulation Of Cellular Component Organization Regulation Of Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase I Regulation Of Organelle Organization Growth Cone Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuron Projection Development Hepatocyte Homeostasis Positive Regulation Of Cell Projection Organization Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Somatic Diversification Of Immunoglobulins Positive Regulation Of Bone Mineralization Regulation Of Transcription By RNA Polymerase I Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Ion Transmembrane Transporter Activity Actin Monomer Sequestering Activity Positive Regulation Of Transporter Activity Positive Regulation Of Neurotrophin Production Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Gamma-tubulin Binding Nucleoplasm Regulation Of Neuron Projection Development Cellular Response To Trichostatin A Regulation Of Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Projection Organization HSP90-CDC37 Chaperone Complex Hypothalamus Gonadotrophin-releasing Hormone Neuron Development System Development Immunoglobulin Heavy Chain V-D-J Recombination Positive Regulation Of Ossification	Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Proteolysis Ubiquitin Protein Ligase Binding Negative Regulation Of Biosynthetic Process Cytosol Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Defense Response Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Response To Lipid Cytoplasm Positive Regulation Of Protein Metabolic Process Regulation Of Interleukin-1 Production Regulation Of Innate Immune Response Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Identical Protein Binding Regulation Of Immune System Process Negative Regulation Of Signal Transduction Nucleus Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Immune Response Regulation Of Multicellular Organismal Process Regulation Of Programmed Cell Death Macromolecule Metabolic Process Regulation Of Interleukin-1 Beta Production Negative Regulation Of Signaling Negative Regulation Of Cell Communication CD95 Death-inducing Signaling Complex Positive Regulation Of Defense Response Catabolic Process
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