TAF1D and FAF1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TAF1D	FAF1
Gene Name		TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	Fas (TNFRSF6) associated factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Microtubule Organizing Center	Nucleus Nuclear Envelope Cytosol CD95 Death-inducing Signaling Complex Cdc48p-Npl4p-Ufd1p AAA ATPase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding	Protein Binding Protein Kinase Regulator Activity Protein Kinase Binding Protein Domain Specific Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding NF-kappaB Binding
	Biological Process	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Apoptotic Process Cytoplasmic Sequestering Of NF-kappaB Cell Death Regulation Of Cell Adhesion Positive Regulation Of Protein Complex Assembly Regulation Of Protein Catabolic Process Positive Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS			Depression and alcohol dependence ( 22064162) Ventricular conduction ( 21076409)
Protein-Protein Interactions		24 interactors: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP NGEF POLB PTN RPL36AL SMARCB1 TAF1A TAF1B TAF1C TMSB4X UBE2D1 UBTF	37 interactors: ANXA1 ANXA7 ASCC2 CASP8 CD40 CDC73 CDKN1A CSNK2A1 CSNK2B DNAJB11 FADD FAF2 FAS HSD17B10 IGF2 IKBKB ITGB1BP1 NGLY1 NLRP12 NLRP2 NLRP3 NLRP7 NR1H2 NR4A1 RAP1A RAP1B RCC1 RELA SIRT6 SKIL SNIP1 TAF1D TK1 TNNT1 TSC22D1 UROD VAPB
Entrez ID		79101	11124
HPRD ID		14679	05124
Ensembl ID		ENSG00000166012	ENSG00000185104
Uniprot IDs		E9PM59 Q9H5J8	B4DEJ6 Q9UNN5
PDB IDs			1H8C 2DZM 2EC4 3E21 3QC8 3QCA 3QQ8 3QWZ 3QX1 3R3M
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Regulation Of Gene Expression, Epigenetic Chromatin Silencing At RDNA Cellular Macromolecule Biosynthetic Process DNA-templated Transcription, Termination Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription, DNA-templated Biosynthetic Process RNA Biosynthetic Process Chromatin Silencing Gene Expression Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Gene Silencing Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Nitrogen Compound Metabolic Process DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Cell Morphogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Osteoclast Maturation Cellular Process Negative Regulation Of Gene Expression Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Cell Cycle Phase Transition	Response To Organic Substance Cellular Response To Organic Substance Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Organic Cyclic Compound Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Hydrolase Activity Response To Lipid Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Steroid Hormone Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Establishment Of Protein Localization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Endopeptidase Activity Signal Transduction Regulation Of Signaling Positive Regulation Of Peptidase Activity Regulation Of Endopeptidase Activity Cellular Response To Mechanical Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Peptidase Activity Response To External Stimulus Regulation Of Protein Localization Regulation Of Cellular Localization Leukocyte Homeostasis Regulation Of Immune System Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Signaling Activation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Protein Kinase Activity Cell Communication Intracellular Receptor Signaling Pathway
Tagcloud ?		abundances dephosphorylations dioxide g2 identifies isotope mitosis phosphorylations player polymerases proteomic silac sl1 speculate stoichiometries taf3 taf4 taf7 tafi41 tafs tata tbp tfiid tfiiib tightly titanium transitions tryptic	agr apo avian caenorhabditis carboxy conjugating delimited e0 elegans executed fas fibroblast helical homologies homologue mesoderm mutagenesis pluripotent portion potentiates qfaf quail remarkable resides shares transducing ubiquitous unusual
Tagcloud (Difference) ?		abundances dephosphorylations dioxide g2 identifies isotope mitosis phosphorylations player polymerases proteomic silac sl1 speculate stoichiometries taf3 taf4 taf7 tafi41 tafs tata tbp tfiid tfiiib tightly titanium transitions tryptic	agr apo avian caenorhabditis carboxy conjugating delimited e0 elegans executed fas fibroblast helical homologies homologue mesoderm mutagenesis pluripotent portion potentiates qfaf quail remarkable resides shares transducing ubiquitous unusual
Tagcloud (Intersection) ?