TAF1D and DDAH2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TAF1D	DDAH2
Description		TATA-box binding protein associated factor, RNA polymerase I subunit D	DDAH family member 2, ADMA-independent
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle	Cytoplasm Mitochondrion Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding Dimethylargininase Activity Hydrolase Activity
	Biological Process	Regulation Of DNA-templated Transcription	Citrulline Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs			Citrulline
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		23 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TMSB4X UBE2D1 UBTF	28 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SCGN SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14
Entrez ID		79101	23564
HPRD ID		14679	09204
Ensembl ID		ENSG00000166012	ENSG00000213722
Uniprot IDs		Q9H5J8	O95865 V9HW53
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Glucose Mediated Signaling Pathway RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Regulation Of Organelle Transport Along Microtubule Regulation Of Stem Cell Differentiation Positive Regulation Of Dendrite Development Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Protein Kinase Regulator Activity Ovulation Cycle Protein-containing Complex Regulation Of Microtubule-based Process Regulation Of Cell Communication Negative Regulation Of Stem Cell Differentiation Regulation Of Signaling Regulation Of Cell Differentiation Positive Regulation Of Cation Channel Activity Regulation Of Cellular Component Organization Regulation Of Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase I Regulation Of Organelle Organization Growth Cone Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuron Projection Development Hepatocyte Homeostasis Positive Regulation Of Cell Projection Organization Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Somatic Diversification Of Immunoglobulins Positive Regulation Of Bone Mineralization Regulation Of Transcription By RNA Polymerase I Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Ion Transmembrane Transporter Activity Actin Monomer Sequestering Activity Positive Regulation Of Transporter Activity Positive Regulation Of Neurotrophin Production Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Gamma-tubulin Binding Nucleoplasm Regulation Of Neuron Projection Development Cellular Response To Trichostatin A Regulation Of Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Projection Organization HSP90-CDC37 Chaperone Complex Hypothalamus Gonadotrophin-releasing Hormone Neuron Development System Development Immunoglobulin Heavy Chain V-D-J Recombination Positive Regulation Of Ossification	Cytoplasm Nucleus Regulation Of Mitotic Cell Cycle Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Kinase Activity Intracellular Signal Transduction Cytosol Regulation Of Cell Cycle Process Protein Kinase Activity JNK Cascade Response To Phorbol 13-acetate 12-myristate Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Positive Regulation Of Programmed Cell Death Epithelial Cell Proliferation Cellular Response To UV-B Protein Phosphorylation Identical Protein Binding Intracellular Signaling Cassette Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Phosphorylation Magnesium Ion Binding Regulation Of Programmed Cell Death Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Cycle Phase Transition Regulation Of Translation In Response To Stress Positive Regulation Of JNK Cascade Response To UV-B Regulation Of Cell Cycle Phase Transition Cellular Response To Gamma Radiation Regulation Of Mitotic Nuclear Division Negative Regulation Of Cell Cycle Process Regulation Of Multicellular Organismal Process Protein Binding Z Disc Phosphate-containing Compound Metabolic Process Signal Transduction Nucleotide Binding ATP Binding Cyclin Binding Regulation Of Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Nuclear Division Cis-trans Isomerase Activity Positive Regulation Of Apoptotic Process Histone H2AS1 Kinase Activity Positive Regulation Of Mitotic DNA Damage Checkpoint
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