TAF1D and UBTF

Number of citations of the paper that reports this interaction (PubMedID 17318177)
43

Data Source:
HPRD (in vitro)

		TAF1D	UBTF
Description		TATA-box binding protein associated factor, RNA polymerase I subunit D	upstream binding transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle	Fibrillar Center Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity DNA Binding Chromatin Binding RNA Binding Protein Binding Scaffold Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription	RNA Polymerase I Preinitiation Complex Assembly Transcription By RNA Polymerase I Transcription Initiation At RNA Polymerase I Promoter Positive Regulation Of Transcription By RNA Polymerase I Regulation Of Glucose Mediated Signaling Pathway
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Diverticular disease ( 30177863) hemolysis of donated blood (osmotic) ( 34014839) Mean corpuscular hemoglobin concentration ( 29403010) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		23 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TMSB4X UBE2D1 UBTF	37 interacting genes: AURKA CCNA2 CCND1 CCNE1 CDK2 CDK4 CEBPA CENPC CHGB CREBBP CSNK2A1 EP300 GSK3A IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E POLR1G RB1 RBL2 RNF10 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 USP7 ZMYM2
Entrez ID		79101	7343
HPRD ID		14679	02814
Ensembl ID		ENSG00000166012	ENSG00000108312
Uniprot IDs		Q9H5J8	P17480
PDB IDs			1K99 1L8Y 1L8Z 2HDZ
Enriched GO Terms of Interacting Partners?		Regulation Of Glucose Mediated Signaling Pathway RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Regulation Of Organelle Transport Along Microtubule Regulation Of Stem Cell Differentiation Positive Regulation Of Dendrite Development Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Protein Kinase Regulator Activity Ovulation Cycle Protein-containing Complex Regulation Of Microtubule-based Process Regulation Of Cell Communication Negative Regulation Of Stem Cell Differentiation Regulation Of Signaling Regulation Of Cell Differentiation Positive Regulation Of Cation Channel Activity Regulation Of Cellular Component Organization Regulation Of Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase I Regulation Of Organelle Organization Growth Cone Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuron Projection Development Hepatocyte Homeostasis Positive Regulation Of Cell Projection Organization Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Somatic Diversification Of Immunoglobulins Positive Regulation Of Bone Mineralization Regulation Of Transcription By RNA Polymerase I Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Ion Transmembrane Transporter Activity Actin Monomer Sequestering Activity Positive Regulation Of Transporter Activity Positive Regulation Of Neurotrophin Production Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Gamma-tubulin Binding Nucleoplasm Regulation Of Neuron Projection Development Cellular Response To Trichostatin A Regulation Of Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Projection Organization HSP90-CDC37 Chaperone Complex Hypothalamus Gonadotrophin-releasing Hormone Neuron Development System Development Immunoglobulin Heavy Chain V-D-J Recombination Positive Regulation Of Ossification	Transcription By RNA Polymerase I DNA-templated Transcription RNA Polymerase Transcription Factor SL1 Complex Nucleoplasm Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleus Transcription Regulator Complex Nucleobase-containing Compound Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process Transcription Initiation At RNA Polymerase I Promoter Regulation Of Cell Cycle Phase Transition Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process RNA Polymerase I Preinitiation Complex Assembly Regulation Of Proteolysis RNA Metabolic Process RNA Polymerase I Transcription Regulator Complex Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Population Proliferation Macromolecule Biosynthetic Process Positive Regulation Of Catabolic Process Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Process Regulation Of RNA Metabolic Process Positive Regulation Of Cell Population Proliferation Cell Division Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleolar Large RRNA Transcription By RNA Polymerase I Cell Cycle Phase Transition Regulation Of Macromolecule Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Protein Catabolic Process Regulation Of Protein Stability Gland Development DNA-binding Transcription Factor Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle
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