HNRNPM and RBM4

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		HNRNPM	RBM4
Gene Name		heterogeneous nuclear ribonucleoprotein M	RNA binding motif protein 4
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nucleolus Integral Component Of Plasma Membrane Membrane Nuclear Matrix Extracellular Matrix Paraspeckles Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytoplasmic Stress Granule Nuclear Speck
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Protein Domain Specific Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding MiRNA Binding Poly(A) RNA Binding Pre-mRNA Intronic Binding Pre-mRNA Intronic Pyrimidine-rich Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	Regulation Of Alternative MRNA Splicing, Via Spliceosome Cap-independent Translational Initiation IRES-dependent Translational Initiation RNA Processing MRNA Processing RNA Splicing Negative Regulation Of Translation Cell Differentiation Negative Regulation Of Translation In Response To Stress Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Translational Initiation Response To Arsenic-containing Substance Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Muscle Cell Differentiation Stress-activated MAPK Cascade Circadian Regulation Of Translation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		19 interactors: AKAP9 APC CEACAM5 GMCL1P1 HNRNPF JUN KIAA0368 LMO2 LMO3 LYST PRRC2A RBM4 RBM4B STAT3 TCERG1 TEKT4 WDR77 YWHAG ZNF207	29 interactors: AQR CCNA1 CDK2 CXorf56 DDX17 DDX5 DGCR14 DHX9 HNRNPF HNRNPH2 HNRNPH3 HNRNPK HNRNPM HNRNPUL1 LRP2BP PABPC1 PRPF31 PTBP2 RBM10 RBM22 RBM23 RBM42 RBM7 SF1 SF3B4 SMAD5 SNRPC TRIB3 U2AF2
Entrez ID		4670	5936
HPRD ID		01188	03982
Ensembl ID		ENSG00000099783	ENSG00000173933
Uniprot IDs		P52272	Q9BWF3
PDB IDs		2DGV 2DH9 2DO0 2OT8	2DNQ
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Cellular Metabolic Process Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development RNA Splicing Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Negative Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Negative Regulation Of Cellular Protein Metabolic Process Circadian Rhythm Regulation Of Myeloid Cell Differentiation Mitotic Spindle Assembly Checkpoint Regulation Of Cellular Protein Metabolic Process Spindle Assembly Checkpoint Gene Expression Negative Regulation Of Protein Metabolic Process Mitotic Spindle Checkpoint Regulation Of Metabolic Process Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation MRNA Metabolic Process Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Protein Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition RNA Processing Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Cellular Response To Potassium Ion Starvation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression Negative Regulation Of Proteasomal Protein Catabolic Process Somatic Stem Cell Maintenance Regulation Of Epithelial Cell Proliferation Negative Regulation Of Cell Proliferation Mitotic Cell Cycle Process Rhythmic Process Negative Regulation Of Cellular Protein Catabolic Process Leading Edge Cell Differentiation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Phosphorylation Regulation Of Chromosome Segregation	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Processing Cellular Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Ribonucleoprotein Complex Assembly Spliceosomal Complex Assembly Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Ribonucleoprotein Complex Biogenesis MRNA Stabilization Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Spliceosomal SnRNP Assembly Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Meiotic Cell Cycle Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression
Tagcloud ?		accumulate almost binds ccnd1 cyclins cytoplasmic d3 depends dramatically drop efficient enriched fall g1 igf2 imp imps indispensable mrnas nucleus numerous origins partner poorly regulators retention transcripts understood unfavorable	ago2 altogether argonaute2 associates c2c12 cap colocalizes cytoplasm deposited entry granules micro micrornas microtubule mrnas myoblast notably participates potentiates recruit ribonucleoprotein ribonucleoproteins ribosome rnas suppress suppresses transiently translation translocates
Tagcloud (Difference) ?		accumulate almost binds ccnd1 cyclins cytoplasmic d3 depends dramatically drop efficient enriched fall g1 igf2 imp imps indispensable nucleus numerous origins partner poorly regulators retention transcripts understood unfavorable	ago2 altogether argonaute2 associates c2c12 cap colocalizes cytoplasm deposited entry granules micro micrornas microtubule myoblast notably participates potentiates recruit ribonucleoprotein ribonucleoproteins ribosome rnas suppress suppresses transiently translation translocates
Tagcloud (Intersection) ?		mrnas