HNRNPM and AKAP9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HNRNPM	AKAP9
Gene Name		heterogeneous nuclear ribonucleoprotein M	A kinase (PRKA) anchor protein 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nucleolus Integral Component Of Plasma Membrane Membrane Nuclear Matrix Extracellular Matrix Paraspeckles Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Pericentriolar Material Golgi Apparatus Centrosome Cytosol Cytoskeleton Voltage-gated Potassium Channel Complex Ciliary Basal Body Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Protein Domain Specific Binding Poly(A) RNA Binding	Receptor Binding Protein Binding Potassium Channel Regulator Activity Protein Complex Scaffold Ion Channel Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Organelle Organization Signal Transduction Synaptic Transmission Spermatogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Sertoli Cell Development Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cellular Response To CAMP Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition CREB phosphorylation through the activation of Ras Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of NMDA receptor upon glutamate binding and postsynaptic events Loss of Nlp from mitotic centrosomes CREB phosphorylation through the activation of CaMKII Centrosome maturation Mitotic G2-G2/M phases Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Recruitment of mitotic centrosome proteins and complexes Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AKAP9 APC CEACAM5 GMCL1P1 HNRNPF JUN KIAA0368 LMO2 LMO3 LYST PRRC2A RBM4 RBM4B STAT3 TCERG1 TEKT4 WDR77 YWHAG ZNF207	43 interactors: BLZF1 C1orf94 CALM1 CALM2 CALM3 CCP110 CDC5L CEP55 CLIC1 CSNK1D CSNK1E DISC1 FNBP1 GRIN1 HNRNPM IKZF3 KCNQ1 KDM1A MAGEA6 MAGED1 PCNT PKN1 PPP1CA PPP2R1B PPP2R3A PRDM14 PRKAR2A PRKAR2B PRKCE SAMD3 SSX2 SUV39H2 TACC3 TDP2 THAP1 TNIK TRIP10 TSG101 TSNAX TUBGCP3 USHBP1 USO1 WAC
Entrez ID		4670	10142
HPRD ID		01188	04921
Ensembl ID		ENSG00000099783	ENSG00000127914
Uniprot IDs		P52272	Q5GIA7 Q6PJH3 Q99996
PDB IDs		2DGV 2DH9 2DO0 2OT8
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Cellular Metabolic Process Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development RNA Splicing Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Negative Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Negative Regulation Of Cellular Protein Metabolic Process Circadian Rhythm Regulation Of Myeloid Cell Differentiation Mitotic Spindle Assembly Checkpoint Regulation Of Cellular Protein Metabolic Process Spindle Assembly Checkpoint Gene Expression Negative Regulation Of Protein Metabolic Process Mitotic Spindle Checkpoint Regulation Of Metabolic Process Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation MRNA Metabolic Process Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Protein Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition RNA Processing Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Cellular Response To Potassium Ion Starvation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression Negative Regulation Of Proteasomal Protein Catabolic Process Somatic Stem Cell Maintenance Regulation Of Epithelial Cell Proliferation Negative Regulation Of Cell Proliferation Mitotic Cell Cycle Process Rhythmic Process Negative Regulation Of Cellular Protein Catabolic Process Leading Edge Cell Differentiation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Phosphorylation Regulation Of Chromosome Segregation	Cell Cycle Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Organelle Organization Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity G2/M Transition Of Mitotic Cell Cycle Regulation Of Cytokinesis Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Neurotrophin Signaling Pathway Regulation Of Signaling Energy Reserve Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Amphetamine Blood Coagulation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Protein Metabolic Process Hemostasis Regulation Of Circadian Rhythm Cell Cycle Process Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Transporter Activity Response To Fibroblast Growth Factor Positive Regulation Of Protein Kinase Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Detection Of Calcium Ion Negative Regulation Of Ion Transmembrane Transport Response To Amine Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Communication By Electrical Coupling Regulation Of Cell Cycle Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Transmembrane Transport Mitotic Cell Cycle Positive Regulation Of Transferase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation
Tagcloud ?		accumulate almost binds ccnd1 cyclins cytoplasmic d3 depends dramatically drop efficient enriched fall g1 igf2 imp imps indispensable mrnas nucleus numerous origins partner poorly regulators retention transcripts understood unfavorable	akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		accumulate almost binds ccnd1 cyclins cytoplasmic d3 depends dramatically drop efficient enriched fall g1 igf2 imp imps indispensable mrnas nucleus numerous origins partner poorly regulators retention transcripts understood unfavorable	akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Intersection) ?