KXD1 and ARHGDIG

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KXD1	ARHGDIG
Gene Name		KxDL motif containing 1	Rho GDP dissociation inhibitor (GDI) gamma
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	BLOC-1 Complex	Cytosol Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Protein Binding	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity
	Biological Process	Vesicle-mediated Transport	Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Regulation Of Protein Localization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: APPL1 ARHGDIG C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 DYRK2 EWSR1 EXOC5 EXOC7 FXR2 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 STX11 TCEB3B TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417	8 interactors: CDC42 CEP170P1 KXD1 RAC1 RHOA RHOB RHOG RHOH
Entrez ID		79036	398
HPRD ID		14526	04163
Ensembl ID		ENSG00000105700	ENSG00000242173
Uniprot IDs		Q9BQD3	F1T0H7 Q99819
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Organelle Assembly Actin-mediated Cell Contraction Actin Filament-based Movement Membrane Organization Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion Mitochondrion Degradation Organelle Disassembly Organelle Organization Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Glucocorticoid Receptor Signaling Pathway DGDP Catabolic Process DADP Catabolic Process Positive Regulation Of Heart Rate By Epinephrine GDP Catabolic Process Opsin Transport Autophagic Vacuole Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Tissue Development Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Macroautophagy Muscle Contraction 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Muscle Tissue Morphogenesis Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Dihydrobiopterin Metabolic Process	Small GTPase Mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Axon Guidance Blood Coagulation Hemostasis Axonogenesis Platelet Activation Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Neuron Projection Morphogenesis Cell Activation Response To Wounding Rho Protein Signal Transduction Cell Morphogenesis Involved In Differentiation Neuron Projection Development Regulation Of Intracellular Signal Transduction Cell Projection Morphogenesis Cell Part Morphogenesis Intracellular Signal Transduction Neuron Development Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Regulation Of Cell Projection Assembly Neuron Differentiation Cell Projection Organization Regulation Of Cell Projection Organization Locomotion Positive Regulation Of Cell Morphogenesis Involved In Differentiation Actin Cytoskeleton Organization Regulation Of Signal Transduction Actin Filament-based Process Movement Of Cell Or Subcellular Component Cell-cell Junction Organization Generation Of Neurons Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Ras Protein Signal Transduction Regulation Of Signaling Neurogenesis Regulation Of Substrate Adhesion-dependent Cell Spreading Cell Development Cell Migration Response To External Stimulus Substantia Nigra Development Positive Regulation Of Cell Projection Organization Cell Differentiation
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